Paclitaxel

ATP-binding cassette, sub-family B (MDR/TAP), member 1B ; Mus musculus







33 Article(s)
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1 31165698 Effective Gene Silencing Mediated by Polypeptide Nanoparticles LAH4-L1-siMDR1 in Multi-Drug Resistant Human Breast Cancer. 2019 Mar 1 2
2 28181548 Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1. 2017 Feb 9 4
3 28265007 The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors. 2017 Jun 9
4 28302530 Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study. 2017 Jun 28 3
5 28796259 MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner. 2017 Aug 10 1
6 26850595 MicroRNA-873 mediates multidrug resistance in ovarian cancer cells by targeting ABCB1. 2016 Aug 2
7 25268938 P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. 2015 Jan 5 1
8 25677062 NSC23925 prevents the emergence of multidrug resistance in ovarian cancer in vitro and in vivo. 2015 Apr 1
9 26075272 Ecdysteroids sensitize MDR and non-MDR cancer cell lines to doxorubicin, paclitaxel, and vincristine but tend to protect them from cisplatin. 2015 1
10 26633878 Fentanyl Enhances Hepatotoxicity of Paclitaxel via Inhibition of CYP3A4 and ABCB1 Transport Activity in Mice. 2015 1
11 23063650 Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models. 2013 Jan 28 1
12 23090875 P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel. 2013 May 15 2
13 24289639 Establishment of paclitaxel-resistant breast cancer cell line and nude mice models, and underlying multidrug resistance mechanisms in vitro and in vivo. 2013 1
14 22842366 Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. 2012 Apr-Jun 1
15 19924122 Intravenous-to-oral switch in anticancer chemotherapy: a focus on docetaxel and paclitaxel. 2010 Jan 1
16 20642825 Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1. 2010 Jul 19 2
17 19821097 Reversal of multi-drug resistance by vector-based-shRNA-mdr1 in vitro and in vivo. 2009 Oct 2
18 17932689 Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. 2008 May 1
19 17331135 Optimization of multidrug resistance 1 gene transfer confers chemoprotection to human hematopoietic cells engrafted in immunodeficient mice. 2007 May 1
20 16544145 Reversal of multidrug resistance by two nordihydroguaiaretic acid derivatives, M4N and maltose-M3N, and their use in combination with doxorubicin or paclitaxel. 2006 Nov 1
21 17062689 Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics. 2006 Oct 15 2
22 16288028 SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells. 2005 Nov 15 2
23 15294454 Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06. 2004 Sep 1 1
24 11862425 Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut. 2002 Feb 1
25 11920652 Genetic protection of repopulating hematopoietic cells with an improved MDR1-retrovirus allows administration of intensified chemotherapy following stem cell transplantation in mice. 2002 Apr 10 1
26 10617675 Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. 2000 Jan 1
27 9698071 A unique interaction between polyamine and multidrug resistance (P-glycoprotein) transporters in cultured Chinese hamster ovary cells transfected with mouse mdr-1 gene. 1998 Jul 15 3
28 9698374 Identification of the domains of photoincorporation of the 3'- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein. 1998 Aug 11 3
29 9446255 [SDZ PSC 833: a novel modulator of MDR]. 1997 Sep-Oct 1
30 22358644 Transfer and expression of the human multiple drug resistance gene as potential human gene therapy. 1995 Jan 3
31 1352414 Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. 1992 Jul 3 1
32 1357667 Transfer and expression of the human multiple drug resistance gene into live mice. 1992 Oct 15 6
33 1868977 Molecular manipulations of the multidrug transporter: a new role for transgenic mice. 1991 Aug 1