49 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34806449 | Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model. | 2022 Jan 1 | 1 |
2 | 32994182 | Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling. | 2021 Jan | 1 |
3 | 33543290 | Metformin: a novel promising option for fertility preservation during cyclophosphamide-based chemotherapy. | 2021 Jan 22 | 4 |
4 | 33575476 | Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways. | 2021 Mar 26 | 1 |
5 | 33609419 | Impact of diabetes on promoting the growth of breast cancer. | 2021 May | 1 |
6 | 33947424 | Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts. | 2021 May 4 | 5 |
7 | 34688695 | Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride. | 2021 Dec 1 | 1 |
8 | 30820523 | Differential Effects of Rapamycin and Metformin in Combination With Rapamycin on Mechanisms of Proteostasis in Cultured Skeletal Myotubes. | 2020 Jan 1 | 1 |
9 | 31818851 | A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index. | 2020 Feb | 4 |
10 | 31874168 | Hyperactive Akt-mTOR pathway as a therapeutic target for pain hypersensitivity in Cntnap2-deficient mice. | 2020 Mar 15 | 1 |
11 | 31904843 | Metformin enhances the immunomodulatory potential of adipose-derived mesenchymal stem cells through STAT1 in an animal model of lupus. | 2020 Jun 1 | 2 |
12 | 31945013 | Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR. | 2020 Jan 16 | 2 |
13 | 32843973 | Diabetes mellitus type 2 drives metabolic reprogramming to promote pancreatic cancer growth. | 2020 Aug | 1 |
14 | 32908958 | The Synergistic Effect of an ATP-Competitive Inhibitor of mTOR and Metformin on Pancreatic Tumor Growth. | 2020 Sep | 1 |
15 | 33099954 | Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. | 2020 Jul-Aug | 2 |
16 | 30779140 | Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7(Nek7) expression. | 2019 Feb 19 | 1 |
17 | 30909226 | Metformin Therapy Aggravates Neurodegenerative Processes in ApoE-/- Mice. | 2019 | 3 |
18 | 30945296 | Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7 (Nek7) expression. | 2019 Sep | 1 |
19 | 30972229 | Effect of a High-Fat Diet and Metformin on Placental mTOR Signaling in Mice. | 2019 Apr | 5 |
20 | 31182921 | Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy. | 2019 | 4 |
21 | 31273547 | Basic Research in Diabetic Nephropathy Health Care: A study of the Renoprotective Mechanism of Metformin. | 2019 Jul 4 | 2 |
22 | 31467666 | Metformin represses the pathophysiology of AAA by suppressing the activation of PI3K/AKT/mTOR/autophagy pathway in ApoE-/- mice. | 2019 | 3 |
23 | 31698699 | Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy. | 2019 Nov 6 | 1 |
24 | 29253574 | Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice. | 2018 Mar | 2 |
25 | 29554968 | Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways. | 2018 Mar 20 | 1 |
26 | 29859833 | Metformin alleviated endotoxemia-induced acute lung injury via restoring AMPK-dependent suppression of mTOR. | 2018 Aug 1 | 3 |
27 | 30025915 | Metformin suppresses growth and adrenocorticotrophic hormone secretion in mouse pituitary corticotroph tumor AtT20 cells. | 2018 Dec 15 | 2 |
28 | 30275441 | Metformin Increases Cardiac Rupture After Myocardial Infarction via the AMPK-MTOR/PGC-1α Signaling Pathway in Rats with Acute Myocardial Infarction. | 2018 Oct 2 | 2 |
29 | 30409193 | Metformin induces apoptosis in mesenchymal stromal cells and dampens their therapeutic efficacy in infarcted myocardium. | 2018 Nov 8 | 1 |
30 | 27803295 | Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis. | 2017 Jan 1 | 1 |
31 | 28242651 | Metformin Suppresses Systemic Autoimmunity in Roquinsan/san Mice through Inhibiting B Cell Differentiation into Plasma Cells via Regulation of AMPK/mTOR/STAT3. | 2017 Apr 1 | 4 |
32 | 28274614 | Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death. | 2017 May 15 | 2 |
33 | 26921394 | High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum. | 2016 Mar | 1 |
34 | 26943960 | Metformin ameliorates the development of experimental autoimmune encephalomyelitis by regulating T helper 17 and regulatory T cells in mice. | 2016 Mar 15 | 1 |
35 | 27223262 | Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer. | 2016 Jun 21 | 1 |
36 | 25456211 | AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell. | 2015 | 1 |
37 | 25576058 | Metformin and Rapamycin Reduce Pancreatic Cancer Growth in Obese Prediabetic Mice by Distinct MicroRNA-Regulated Mechanisms. | 2015 May | 1 |
38 | 25879666 | Metformin suppresses diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-+Leprdb/+Leprdb mice. | 2015 | 1 |
39 | 25909163 | Metformin potentiates rapamycin and cisplatin in gastric cancer in mice. | 2015 May 20 | 1 |
40 | 23949159 | Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice. | 2014 Feb | 3 |
41 | 24905037 | Therapeutic potential of metformin in papillary thyroid cancer in vitro and in vivo. | 2014 Aug 5 | 1 |
42 | 24466367 | Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling. | 2013 Dec 1 | 1 |
43 | 22378068 | Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy. | 2012 Mar 1 | 1 |
44 | 21465524 | Metformin sensitizes insulin signaling through AMPK-mediated PTEN down-regulation in preadipocyte 3T3-L1 cells. | 2011 May | 2 |
45 | 21543517 | Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth. | 2011 Jun 15 | 2 |
46 | 20363874 | AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. | 2010 Jun | 1 |
47 | 20564343 | Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase. | 2010 Jul | 2 |
48 | 20810672 | Metformin prevents tobacco carcinogen--induced lung tumorigenesis. | 2010 Sep | 7 |
49 | 19501448 | Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia. | 2009 Aug | 1 |