Pub. Date : 2011 May
PMID : 21465524
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Both pharmacologic inhibition and knock-down of AMPK blocked metformin-induced phosphorylation of JNK and mTOR. | Metformin | mechanistic target of rapamycin kinase | Mus musculus |
| 2 | PTEN promoter activity was suppressed by metformin and inhibition of mTOR and JNK by pharmacologic inhibitors blocked metformin-induced PTEN promoter activity suppression. | Metformin | mechanistic target of rapamycin kinase | Mus musculus |