Title : Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways.

Pub. Date : 2018 Mar 20

PMID : 29554968






1 Functional Relationships(s)
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1 The xenograft mouse model further confirmed that metformin inhibited tumor growth by upregulation of AMPK and downregulation of mTOR. Metformin mechanistic target of rapamycin kinase Mus musculus