Organophosphates

paraoxonase 1 ; Homo sapiens







165 Article(s)
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51 23894162 Methods for measuring serum activity levels of the 192 Q and R isoenzymes of paraoxonase 1 in QR heterozygous individuals. 2013 Aug 2
52 24123308 Characterization of human paraoxonase 1 variants suggest that His residues at 115 and 134 positions are not always needed for the lactonase/arylesterase activities of the enzyme. 2013 Dec 2
53 24163803 Correlation between Cholinesterase and Paraoxonase 1 Activities:Case Series of Pesticide Poisoning Subjects. 2013 3
54 20947215 Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases. 2012 Jan 2
55 21867409 The human paraoxonase gene cluster as a target in the treatment of atherosclerosis. 2012 Mar 15 1
56 22193970 Docking and molecular dynamics simulation studies on glycation-induced conformational changes of human paraoxonase 1. 2012 Feb 1
57 22301377 Crossroads in the evaluation of paraoxonase 1 for protection against nerve agent and organophosphate toxicity. 2012 Apr 5 3
58 22414384 Polyethylene glycosylation prolongs the stability of recombinant human paraoxonase-1. 2012 May 5 4
59 22683313 Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community. 2012 Aug 2
60 22704918 Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease. 2012 Jul 26 2
61 22760442 Cholinesterase and paraoxonase (PON1) enzyme activities in Mexican-American mothers and children from an agricultural community. 2012 Nov 2
62 22901080 Ultrasensitive assay for detection of serum paraoxonase by modulating the growth of fluorescent semiconductor nanoparticles. 2012 Sep 18 1
63 22971832 In vitro inhibition effect of some dihydroxy coumarin compounds on purified human serum paraoxonase 1 (PON1). 2012 Nov 2
64 23001316 In vitro effects of three antidepressant drugs on plasma paraoxonase activity. 2012 2
65 23946555 Mechanistic Insights into the Hydrolysis of Organophosphorus Compounds by Paraoxonase-1: Exploring the Limits of Substrate Tolerance in a Promiscuous Enzyme. 2012 Dec 1
66 20803562 CHO cell expression, long-term stability, and primate pharmacokinetics and brain uptake of an IgG-paroxonase-1 fusion protein. 2011 Jan 1
67 20839225 Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. 2011 Mar 2
68 20934178 The three-gene paraoxonase family: physiologic roles, actions and regulation. 2011 Jan 1
69 20967607 Linking emulsion PCR haplotype analysis. 2011 2
70 21123122 Differential hydrolysis of homocysteine thiolactone by purified human serum (192)Q and (192)R PON1 isoenzymes. 2011 Jan 1 2
71 21219877 Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs. 2011 Mar 15 2
72 21291901 Paraoxonase-1 genetic polymorphisms and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides. 2011 Apr 15 3
73 21382471 In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates. 2011 Jun 3
74 21507778 Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. 2011 Aug 2
75 21786069 Serum paraoxonase-1 (PON-1) genotype and exposure to organophosphorous insectides--is there a high-risk population? 2011 Sep 1
76 21864557 Role of paraoxonase 1 (PON1) in organophosphate metabolism: implications in neurodegenerative diseases. 2011 Nov 1 3
77 21975240 [Paraoxonase: its multiple functions and pharmacological regulation]. 2011 Jul-Sep 2
78 22086792 Naringenin is an inhibitor of human serum paraoxonase (PON1): an in vitro study. 2011 Nov 2
79 19907334 Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease. 2010 Jan 4
80 20045427 Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes. 2010 Apr 15 2
81 20096260 A homogeneous cell-based assay for measurement of endogenous paraoxonase 1 activity. 2010 May 1 2
82 20122908 Lactonases with organophosphatase activity: structural and evolutionary perspectives. 2010 Sep 6 1
83 20221879 The effect of HDL mimetic peptide 4F on PON1. 2010 2
84 20303930 Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers. 2010 Sep 6 2
85 20488557 Decreased serum arylesterase activity in autism spectrum disorders. 2010 Dec 30 2
86 20510879 Estradiol enhances cell-associated paraoxonase 1 (PON1) activity in vitro without altering PON1 expression. 2010 Jul 2 1
87 20535264 Paraoxonase: Its antiatherogenic role in chronic renal failure. 2010 Jan 2
88 20582942 Paraoxonase gene mutations in amyotrophic lateral sclerosis. 2010 Jul 2
89 20670621 Some cardiovascular therapeutics inhibit paraoxonase 1 (PON1) from human serum. 2010 Oct 25 1
90 20691716 Interaction between organophosphate pesticide exposure and PON1 activity on thyroid function. 2010 Nov 15 5
91 21031563 Paraoxonase 1 polymorphisms and haplotypes and the risk for having offspring affected with spina bifida in Southeast Mexico. 2010 Nov 2
92 21040699 Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1. 2010 Dec 3 2
93 21118365 Continuous reduction of plasma paraoxonase activity with increasing dialysis vintage in hemodialysis patients. 2010 Dec 2
94 21126941 PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in utero. 2010 Dec 3
95 19135476 Distribution of PON1 polymorphisms PON1Q192R and PON1L55M among Chinese, Malay and Indian males in Singapore and possible susceptibility to organophosphate exposure. 2009 Mar 1
96 19446239 Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides. 2009 Jul 24 4
97 19577563 Evaluation of the impacts of antibiotic drugs on PON 1; a major bioscavenger against cardiovascular diseases. 2009 Sep 1 2
98 19646734 Maternal exposure to floricultural work during pregnancy, PON1 Q192R polymorphisms and the risk of low birth weight. 2009 Oct 15 1
99 19651761 The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or INCHIANTI studies. 2009 Oct 3
100 19672401 Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners? 2009 Aug 2