Title : Mechanistic Insights into the Hydrolysis of Organophosphorus Compounds by Paraoxonase-1: Exploring the Limits of Substrate Tolerance in a Promiscuous Enzyme.

Pub. Date : 2012 Dec

PMID : 23946555






1 Functional Relationships(s)
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1 We designed, synthesized and screened a library of analogs of the organophosphate pesticide metabolite paraoxon against a recombinant variant of human serum paraoxonase-1. Organophosphates paraoxonase 1 Homo sapiens