Title : NK cell-mediated antibody-dependent cellular cytotoxicity is enhanced by tamoxifen in HER2/neu non-amplified, but not HER2/neu-amplified, breast cancer cells.

Pub. Date : 2016 Nov

PMID : 27573917






5 Functional Relationships(s)
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Protein Name
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1 NK cell-mediated antibody-dependent cellular cytotoxicity is enhanced by tamoxifen in HER2/neu non-amplified, but not HER2/neu-amplified, breast cancer cells. Tamoxifen erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 NK cell-mediated antibody-dependent cellular cytotoxicity is enhanced by tamoxifen in HER2/neu non-amplified, but not HER2/neu-amplified, breast cancer cells. Tamoxifen erb-b2 receptor tyrosine kinase 2 Homo sapiens
3 In this study, tamoxifen was used to increase HER2/neu protein level to determine whether increased tumor antigen expression could enhance NK cell-mediated antibody-dependent cytotoxicity (ADCC). Tamoxifen erb-b2 receptor tyrosine kinase 2 Homo sapiens
4 Tamoxifen was found to increase HER2/neu 1.5-fold to threefold in breast cancer cell lines that were HER2/neu non-amplified. Tamoxifen erb-b2 receptor tyrosine kinase 2 Homo sapiens
5 Tamoxifen was found to increase HER2/neu 1.5-fold to threefold in breast cancer cell lines that were HER2/neu non-amplified. Tamoxifen erb-b2 receptor tyrosine kinase 2 Homo sapiens