Pub. Date : 2016 Jul
PMID : 26884313
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Roles of the ER-alpha36-EGFR/HER2 positive regulatory loops in tamoxifen resistance. | Tamoxifen | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 2 | Extensive researches were conducted to understand the molecular mechanisms involved in tamoxifen resistance, and have revealed that multiple signaling molecules and pathways such as EGFR and HER2 are involved in tamoxifen resistance. | Tamoxifen | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 3 | Extensive researches were conducted to understand the molecular mechanisms involved in tamoxifen resistance, and have revealed that multiple signaling molecules and pathways such as EGFR and HER2 are involved in tamoxifen resistance. | Tamoxifen | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 4 | In this review, we will discuss the biological function and the possible underlying mechanisms of ER-alpha36 in tamoxifen resistance and specifically illustrate a novel cross-talk mechanism; positive regulatory loops between the ER-alpha36 and EGFR/HER2 in tamoxifen resistance. | Tamoxifen | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 5 | In this review, we will discuss the biological function and the possible underlying mechanisms of ER-alpha36 in tamoxifen resistance and specifically illustrate a novel cross-talk mechanism; positive regulatory loops between the ER-alpha36 and EGFR/HER2 in tamoxifen resistance. | Tamoxifen | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |