geranylgeranyl pyrophosphate

3-hydroxy-3-methylglutaryl-CoA reductase ; Homo sapiens







14 Article(s)
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Pub. Year
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1 34368857 Functional study of SCCD pathogenic gene UBIAD1 (Review). 2021 Oct 2
2 34621019 CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer. 2021 Dec 2
3 34842525 Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1. 2021 Nov 29 1
4 30899443 Statins affect human glioblastoma and other cancers through TGF-β inhibition. 2019 Mar 1 1
5 29167270 UbiA prenyltransferase domain-containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids. 2018 Jan 5 2
6 27133418 Potential of tocotrienols in the prevention and therapy of Alzheimer's disease. 2016 May 1
7 25497898 Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation. 2015 Jan 2
8 26425463 Pleiotropic effects of statins. 2015 Sep-Oct 1
9 22960596 Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway. 2013 Feb 1 2
10 22492974 Simvastatin decreases invasiveness of human endometrial stromal cells. 2012 Jul 2
11 21586555 Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation. 2011 Aug 4
12 17666454 Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma. 2008 Jan 2
13 18625202 HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway. 2008 Sep 19 3
14 14598891 Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor. 2003 1