Methoxsalen

cytochrome P450 family 2 subfamily A member 6 ; Homo sapiens







26 Article(s)
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1 23884323 Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor. 2014 Jan 1
2 24475091 Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6) allelic variants CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22: differential susceptibility due to different sequence locations of the mutations. 2014 9
3 24859605 Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice. 2014 Oct 2
4 24086543 Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet A (PUVA) sensitivity. 2013 1
5 22696418 Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes. 2012 Sep 1
6 21244437 Inhibition of cytochrome P450 2A participating in coumarin 7-hydroxylation in pig liver microsomes. 2011 Oct 1
7 19702528 Structure, function, regulation and polymorphism of human cytochrome P450 2A6. 2009 Sep 1
8 21475870 8-Methoxypsoralen, a potent human CYP2A6 inhibitor, inhibits lung adenocarcinoma development induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. 2009 Jul-Aug 6
9 18215451 Different modes of inhibition of mouse Cyp2a5 and rat CYP2A3 by the food-derived 8-methoxypsoralen. 2008 Mar 2
10 18813816 Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J female mice. 2008 Oct 2
11 17021260 Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice. 2007 Jan 2
12 15893417 Dose dependent inhibitory effects of dietary 8-methoxypsoralen on NNK-induced lung tumorigenesis in female A/J mice. 2006 Mar 28 3
13 16086027 Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. 2005 Sep 1
14 16176798 Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk. 2005 Dec 9 1
15 14633670 Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. 2003 Nov 15 4
16 15618749 The contribution of cytochrome P450 to the metabolism of tegafur in human liver. 2003 1
17 11353760 Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro. 2001 Jun 4
18 11506127 Halothane-dependent lipid peroxidation in human liver microsomes is catalyzed by cytochrome P4502A6 (CYP2A6). 2001 Aug 2
19 10611136 Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity. 2000 Jan 7
20 10911933 Mimicking gene defects to treat drug dependence. 2000 1
21 10583023 Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin. 1999 Oct 1
22 9143352 Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. 1997 May 1 4
23 9394031 Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. 1997 Dec 1
24 8819299 Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. 1996 Jul 2
25 8863822 Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants. 1996 Oct 1
26 7945434 Metabolic interactions of methoxsalen and coumarin in humans and mice. 1994 Oct 7 4