Title : Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.

Pub. Date : 1997 May 1

PMID : 9143352






4 Functional Relationships(s)
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1 One of the most potent inhibitors of coumarin 7-hydroxylase was 8-methoxypsoralen (methoxsalen), which was determined to be a mechanism-based inhibitor (suicide substrate) of CYP2A6 (k(inactivation) 0.5 min-1). Methoxsalen cytochrome P450 family 2 subfamily A member 6 Homo sapiens
2 One of the most potent inhibitors of coumarin 7-hydroxylase was 8-methoxypsoralen (methoxsalen), which was determined to be a mechanism-based inhibitor (suicide substrate) of CYP2A6 (k(inactivation) 0.5 min-1). Methoxsalen cytochrome P450 family 2 subfamily A member 6 Homo sapiens
3 One of the most potent inhibitors of coumarin 7-hydroxylase was 8-methoxypsoralen (methoxsalen), which was determined to be a mechanism-based inhibitor (suicide substrate) of CYP2A6 (k(inactivation) 0.5 min-1). Methoxsalen cytochrome P450 family 2 subfamily A member 6 Homo sapiens
4 One of the most potent inhibitors of coumarin 7-hydroxylase was 8-methoxypsoralen (methoxsalen), which was determined to be a mechanism-based inhibitor (suicide substrate) of CYP2A6 (k(inactivation) 0.5 min-1). Methoxsalen cytochrome P450 family 2 subfamily A member 6 Homo sapiens