Pub. Date : 2009 Jul-Aug
PMID : 21475870
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 8-Methoxypsoralen, a potent human CYP2A6 inhibitor, inhibits lung adenocarcinoma development induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. | Methoxsalen | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
2 | Previously, we demonstrated that 8-methoxypsoralen (methoxsalen), a potent human cytochrome P450 2A6 (CYP2A6) inhibitor, strongly suppresses lung adenoma induction by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice. | Methoxsalen | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
3 | Previously, we demonstrated that 8-methoxypsoralen (methoxsalen), a potent human cytochrome P450 2A6 (CYP2A6) inhibitor, strongly suppresses lung adenoma induction by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice. | Methoxsalen | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
4 | Previously, we demonstrated that 8-methoxypsoralen (methoxsalen), a potent human cytochrome P450 2A6 (CYP2A6) inhibitor, strongly suppresses lung adenoma induction by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice. | Methoxsalen | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
5 | Previously, we demonstrated that 8-methoxypsoralen (methoxsalen), a potent human cytochrome P450 2A6 (CYP2A6) inhibitor, strongly suppresses lung adenoma induction by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice. | Methoxsalen | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
6 | These results clearly demonstrate that methoxsalen, a potent human CYP2A6 inhibitor, inhibits not only lung adenoma but also adenocarcinoma development. | Methoxsalen | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |