| 1 |
31199148 | Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors. | 2019 Jul 25 |
2 |
| 2 |
29303363 | Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma. | 2018 Jan |
1 |
| 3 |
29382206 | TOF-SIMS analysis of an isocitrate dehydrogenase 1 mutation-associated oncometabolite in cancer cells. | 2018 Jan 30 |
1 |
| 4 |
29670690 | Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers. | 2018 Apr 12 |
1 |
| 5 |
29743236 | IDH1 Arg-132 mutant promotes tumor formation through down-regulating p53. | 2018 Jun 22 |
1 |
| 6 |
30194083 | Bridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas. | 2018 Sep-Oct |
1 |
| 7 |
27406240 | Point mutation (R153H or R153C) in Escherichia coli isocitrate dehydrogenase: Biochemical characterization and functional implication. | 2017 Jan |
2 |
| 8 |
26188014 | Isocitrate dehydrogenase mutations in gliomas. | 2016 Jan |
1 |
| 9 |
26967252 | Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes. | 2016 Apr 12 |
1 |
| 10 |
27956631 | The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development. | 2016 Dec 27 |
2 |
| 11 |
25324168 | Specific monoclonal antibodies against IDH1/2 mutations as diagnostic tools for gliomas. | 2015 Jan |
3 |
| 12 |
25787993 | Isocitrate dehydrogenase mutations: new opportunities for translational research. | 2015 May |
1 |
| 13 |
25853107 | Identification of a new selective chemical inhibitor of mutant isocitrate dehydrogenase-1. | 2015 Mar |
3 |
| 14 |
26147657 | Role of isocitrate dehydrogenase 1/2 (IDH 1/2) gene mutations in human tumors. | 2015 Oct |
2 |
| 15 |
26198745 | Glandular differentiation in dedifferentiated chondrosarcoma: molecular evidence of a rare phenomenon. | 2015 Sep |
1 |
| 16 |
23235339 | Immunohistochemical demonstration of isocitrate dehydrogenase 1 (IDH1) mutation in a small subset of prostatic carcinomas. | 2014 Apr |
1 |
| 17 |
24590270 | Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation. | 2014 Jun |
1 |
| 18 |
24626950 | Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor-κB activation in a hypoxia-inducible factor 1-α dependent manner. | 2014 May |
2 |
| 19 |
24898068 | Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone. | 2014 Jun |
4 |
| 20 |
23264629 | The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization. | 2013 Feb 8 |
3 |
| 21 |
21996744 | Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production. | 2012 May 10 |
1 |
| 22 |
22238332 | Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy. | 2012 Jan 11 |
1 |
| 23 |
22396072 | Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. | 2012 Jul |
2 |
| 24 |
22442146 | Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation. | 2012 Apr 27 |
1 |
| 25 |
22809434 | Mutation analysis of isocitrate dehydrogenase in acute lymphoblastic leukemia. | 2012 Aug |
1 |
| 26 |
22904127 | IDH1 mutations in diffusely infiltrating astrocytomas: grade specificity, association with protein expression, and clinical relevance. | 2012 Aug |
1 |
| 27 |
23090985 | Detection of 2-hydroxyglutaric acid in vivo by proton magnetic resonance spectroscopy in U87 glioma cells overexpressing isocitrate dehydrogenase-1 mutation. | 2012 Dec |
1 |
| 28 |
23267435 | Promoter Methylation Analysis of IDH Genes in Human Gliomas. | 2012 |
1 |
| 29 |
21352804 | Establishment of a novel monoclonal antibody SMab-1 specific for IDH1-R132S mutation. | 2011 Mar 25 |
2 |
| 30 |
21647154 | IDH1 and IDH2 mutations in pediatric acute leukemia. | 2011 Oct |
1 |
| 31 |
20142433 | Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. | 2010 Feb 15 |
1 |
| 32 |
20513808 | Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. | 2010 Jul 7 |
1 |
| 33 |
20692206 | IDH mutations in glioma and acute myeloid leukemia. | 2010 Sep |
1 |
| 34 |
23905201 | ML309: A potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells | 2010 |
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