Pub. Date : 2014 Jun
PMID : 24898068
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The IDH mutations are remarkably specific to arginine 132 (R132) in IDH1 and arginine 172 (R172) or arginine 140 (R140) in IDH2; IDH1/2 mutations are known to convert alpha-ketoglutarate to oncometabolite R(-)-2-hydroxyglutarate. | Arginine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 2 | The IDH mutations are remarkably specific to arginine 132 (R132) in IDH1 and arginine 172 (R172) or arginine 140 (R140) in IDH2; IDH1/2 mutations are known to convert alpha-ketoglutarate to oncometabolite R(-)-2-hydroxyglutarate. | Arginine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 3 | The IDH mutations are remarkably specific to arginine 132 (R132) in IDH1 and arginine 172 (R172) or arginine 140 (R140) in IDH2; IDH1/2 mutations are known to convert alpha-ketoglutarate to oncometabolite R(-)-2-hydroxyglutarate. | Arginine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 4 | The IDH mutations are remarkably specific to arginine 132 (R132) in IDH1 and arginine 172 (R172) or arginine 140 (R140) in IDH2; IDH1/2 mutations are known to convert alpha-ketoglutarate to oncometabolite R(-)-2-hydroxyglutarate. | Arginine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |