AGI-5198

isocitrate dehydrogenase (NADP(+)) 1 ; Homo sapiens







12 Article(s)
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1 30266754 RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer. 2019 Feb 1
2 31139406 Isocitrate dehydrogenase 1-mutated cancers are sensitive to the green tea polyphenol epigallocatechin-3-gallate. 2019 1
3 31160965 Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes. 2019 1
4 29366652 Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors. 2018 Feb 15 1
5 29382206 TOF-SIMS analysis of an isocitrate dehydrogenase 1 mutation-associated oncometabolite in cancer cells. 2018 Jan 30 1
6 29879375 IDH1-mutant cancer cells are sensitive to cisplatin and an IDH1-mutant inhibitor counteracts this sensitivity. 2018 Jun 7 1
7 30156013 Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1. 2018 Nov 1
8 25778530 Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish. 2015 May 7 1
9 25980580 Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype. 2015 May 20 1
10 26363012 Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198. 2015 Nov 15 3
11 26368816 Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells. 2015 2
12 23558169 An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. 2013 May 3 1