Title : Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1.

Pub. Date : 2018 Nov

PMID : 30156013






1 Functional Relationships(s)
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1 In addition, AGI-5198, a selective inhibitor of mutant IDH1 partially reversed the decrease in viability after JQ1 treatment and also suppressed the JQ1-induced apoptosis in RBE cells. AGI-5198 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens