interleukin 6 signal transducer ; Mus musculus






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1 1988285 Retinoids enhance lectin binding to gp130, a glycoprotein of NIH-3T3 cells: correlation with cell growth and adhesion. Exp Cell Res 1991 Feb 7
2 6652064 Occurrence of alpha-D-galactosyl-containing glycoproteins on Ehrlich tumor cell membranes. Biochemistry 1983 Nov 8 2
3 7539136 Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci U S A 1995 May 23 1
4 8134389 Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130. Proc Natl Acad Sci U S A 1994 Mar 15 3
5 8174677 Identification of a 130-kilodalton tyrosine-phosphorylated protein induced by interleukin-11 as JAK2 tyrosine kinase, which associates with gp130 signal transducer. Exp Hematol 1994 May 1
6 8265649 Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. Proc Natl Acad Sci U S A 1993 Dec 15 1
7 8884986 Leukemia inhibitory factor induces a hypertrophic response mediated by gp130 in murine cardiac myocytes. Res Commun Mol Pathol Pharmacol 1996 Aug 1
8 9003804 Overlapping and distinct signals through leptin receptor (OB-R) and a closely related cytokine signal transducer, gp130. FEBS Lett 1997 Jan 13 1
9 9122220 Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130. Proc Natl Acad Sci U S A 1997 Mar 18 2
10 9253712 Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development. J Mol Med (Berl) 1997 Jul 1
11 9295319 Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex. J Biol Chem 1997 Sep 19 1
12 9329961 Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow. J Clin Invest 1997 Oct 15 5
13 10364425 Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev Biol 1999 Jun 1 1
14 10428964 STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 1999 Aug 2 2
15 10623831 The cytoplasmic tyrosine motifs in full-length glycoprotein 130 have different roles in IL-6 signal transduction. J Immunol 2000 Jan 15 6
16 10811661 Phosphorylation of human gp130 at Ser-782 adjacent to the Di-leucine internalization motif. Effects on expression and signaling. J Biol Chem 2000 Jul 21 1
17 11710439 Stage- and tissue-specific expression of a beta-1,4-galactosyltransferase in the embryonic epidermis. In Vitro Cell Dev Biol Anim 2001 Oct 2
18 11737194 Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited. Eur J Biochem 2001 Dec 1
19 11803046 Inverse regulation of interleukin-6 (IL-6) and IL-6 receptor in histamine deficient histidine decarboxylase-knock-out mice. Immunol Lett 2002 Mar 1 1
20 11820727 The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice. Arch Dermatol Res 2001 Nov 1
21 11830592 Pax3 down-regulation and shut-off of melanogenesis in melanoma B16/F10.9 by interleukin-6 receptor signaling. J Biol Chem 2002 Apr 26 1
22 12070777 Tyrosine 759 of the cytokine receptor gp130 is involved in Listeria monocytogenes susceptibility. Genes Immun 2002 May 5
23 12097503 The Role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system. J Neurosci 2002 Jul 1 2
24 12203823 Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy. Mol Reprod Dev 2002 Oct 2
25 12239166 Heparin acts synergistically with interleukin-11 to induce STAT3 activation and in vitro osteoclast formation. Blood 2002 Oct 1 1
26 12370259 A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis. J Exp Med 2002 Oct 7 3
27 12417753 Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130. Proc Natl Acad Sci U S A 2002 Nov 12 1
28 12817006 TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex. J Immunol 2003 Jul 1 3
29 14603524 Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. J Cell Physiol 2004 Feb 1
30 14617570 Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro. Endocrinology 2004 Mar 3
31 14749363 Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression. Mol Cell Biol 2004 Feb 3
32 14978019 The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis. Int Immunol 2004 Mar 1
33 15292206 Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK. J Biol Chem 2004 Oct 15 1
34 15538938 Involvement of the gp130 cytokine transducer in MtT/S pituitary somatotroph tumour development in an autocrine-paracrine model. Eur J Endocrinol 2004 Nov 1
35 15804043 Local delivery of soluble interleukin-6 receptors to improve the outcome of alpha-toxin producing Staphylococcus aureus infection in mice. Immunobiology 2005 1
36 16036214 Calmodulin-dependent protein kinases phosphorylate gp130 at the serine-based dileucine internalization motif. Biochim Biophys Acta 2005 Aug 1 4
37 16098488 Preferential differentiation of neural progenitor cells into the glial lineage through gp130 signaling in N-methyl-D-aspartate-treated retinas. Brain Res 2005 Sep 7 3
38 16143138 Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130. Gastroenterology 2005 Sep 1
39 17064687 Inhibitory effects of homeodomain-interacting protein kinase 2 on the aorta-gonad-mesonephros hematopoiesis. Exp Cell Res 2007 Jan 1 1
40 17493959 IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state. Int Immunol 2007 Jun 4
41 17889310 Acute alcohol intake impairs lung inflammation by changing pro- and anti-inflammatory mediator balance. Alcohol 2007 Aug 1
42 18714032 Gp130 signaling promotes development of acute experimental colitis by facilitating early neutrophil/macrophage recruitment and activation. J Immunol 2008 Sep 1 1
43 19228423 Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice. BMC Musculoskelet Disord 2009 Feb 19 2
44 19420014 Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicol Sci 2009 Jul 4
45 19501045 N-glycans modulate the activation of gp130 in mouse embryonic neural precursor cells. Biochem Biophys Res Commun 2009 Aug 14 7
46 19592611 Absence of gp130 in dopamine beta-hydroxylase-expressing neurons leads to autonomic imbalance and increased reperfusion arrhythmias. Am J Physiol Heart Circ Physiol 2009 Sep 1
47 19880537 Infarction-induced cytokines cause local depletion of tyrosine hydroxylase in cardiac sympathetic nerves. Exp Physiol 2010 Feb 1
48 20215335 Zinc suppresses Th17 development via inhibition of STAT3 activation. Int Immunol 2010 May 1
49 20348091 Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. J Biol Chem 2010 May 21 1
50 20382701 Lack of glycoprotein 130/signal transducer and activator of transcription 3-mediated signaling in hepatocytes enhances chronic liver injury and fibrosis progression in a model of sclerosing cholangitis. Am J Pathol 2010 May 2