pterin-4 alpha-carbinolamine dehydratase 1 ; Homo sapiens






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1 1698980 Mechanism of action of GABA on intracellular pH and on surface pH in crayfish muscle fibres. J Physiol 1990 Aug 8
2 1913972 Bioactivation of xenobiotics by prostaglandin H synthase. Chem Biol Interact 1991 9
3 1953354 Prostaglandin H synthase dependent metabolism of diethylstilbestrol by ram seminal vesicle cell cultures. Arch Toxicol 1991 7
4 2495173 Arachidonic acid-dependent peroxidative activation of carcinogenic arylamines by extrahepatic human tissue microsomes. Cancer Res 1989 Apr 15 13
5 2495865 Indanyl analogs of diethylstilbestrol: differential interaction with prostaglandin H synthase. Carcinogenesis 1989 May 24
6 3151503 Prostaglandin-H-synthase competent cells derived from ram seminal vesicles: a tool for studying cooxidation of xenobiotics. Mol Toxicol 1987-1988 Fall 1
7 3917545 Inactivation of prostaglandin H synthase and prostacyclin synthase by phenylbutazone. Requirement for peroxidative metabolism. Mol Pharmacol 1985 Jan 16
8 3921273 Formation of thioether conjugates of the bladder carcinogen ANFT catalyzed by prostaglandin H synthase. Carcinogenesis 1985 Apr 3
9 6418878 Prostaglandin H synthase-catalyzed activation of benzidine: a model to assess pharmacologic intervention of the initiation of chemical carcinogenesis. J Pharmacol Exp Ther 1983 Dec 11
10 6428769 Prostaglandin H synthase-dependent co-oxygenation of (+/-)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene in hamster trachea and human bronchus explants. Carcinogenesis 1984 Jul 5
11 7725101 Crystal structure of DCoH, a bifunctional, protein-binding transcriptional coactivator. Science 1995 Apr 28 1
12 7744010 Three-dimensional structure of the bifunctional protein PCD/DCoH, a cytoplasmic enzyme interacting with transcription factor HNF1. EMBO J 1995 May 1 3
13 8001680 Crystallization and preliminary crystallographic studies of recombinant dimerization cofactor of transcription factor HNF1/pterin-4 alpha-carbinolamine dehydratase from liver. FEBS Lett 1995 Jan 2 4
14 8188266 Chromosomal location of two human genes encoding tetrahydrobiopterin-metabolizing enzymes: 6-pyruvoyl-tetrahydropterin synthase maps to 11q22.3-q23.3, and pterin-4 alpha-carbinolamine dehydratase maps to 10q22. Genomics 1994 Jan 15 3
15 8236278 Prostaglandin-H synthase containing cell lines as tools for studying metabolism and toxicity of xenobiotics. Toxicology 1993 Oct 5 1
16 8451760 SEMV cell cultures: a model for studies of prostaglandin-H synthase-mediated metabolism and genotoxicity of xenobiotics. Toxicol Lett 1993 Apr 9
17 8554621 Activity of the bifunctional protein 4a-hydroxy-tetrahydropterin dehydratase/DCoH during human fetal development: correlation with dihydropteridine reductase activity and tetrahydrobiopterin levels. Biochem Biophys Res Commun 1995 Dec 26 2
18 8995521 The bifunctional protein DCoH modulates interactions of the homeodomain transcription factor HNF1 with nucleic acids. J Mol Biol 1997 Jan 10 1
19 9391049 Studies on the enzymatic and transcriptional activity of the dimerization cofactor for hepatocyte nuclear factor 1. Proc Natl Acad Sci U S A 1997 Dec 9 1
20 9465044 Identification of hepatic nuclear factor 1 binding sites in the 5' flanking region of the human phenylalanine hydroxylase gene: implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system. Proc Natl Acad Sci U S A 1998 Feb 17 6
21 9585615 Hyperphenylalaninemia with high levels of 7-biopterin is associated with mutations in the PCBD gene encoding the bifunctional protein pterin-4a-carbinolamine dehydratase and transcriptional coactivator (DCoH). Am J Hum Genet 1998 Jun 6
22 9698371 Stereospecificity and catalytic function of histidine residues in 4a-hydroxy-tetrahydropterin dehydratase/DCoH. Biochemistry 1998 Aug 11 3
23 9894810 Pterin-4a-carbinolamine dehydratase from Pseudomonas aeruginosa: characterization, catalytic mechanism and comparison to the human enzyme. Biol Chem 1998 Dec 1
24 10098606 Characterization of expression of the gene for human pterin carbinolamine dehydratase/dimerization cofactor of HNF1. DNA Cell Biol 1999 Mar 2
25 10217769 PhhB, a Pseudomonas aeruginosa homolog of mammalian pterin 4a-carbinolamine dehydratase/DCoH, does not regulate expression of phenylalanine hydroxylase at the transcriptional level. J Bacteriol 1999 May 2
26 10329684 Peroxygenase metabolism of N-acetylbenzidine by prostaglandin H synthase. Formation of an N-hydroxylamine. J Biol Chem 1999 May 21 5
27 10667392 Prostaglandin H synthase and lipoxygenase mediated activation of xenobiotics in platelets. Adv Exp Med Biol 1999 9
28 10880215 Phosphatase-triggered guest release from a cyclodextrin complex. Org Lett 2000 Jun 15 2
29 10924272 Hyperphenylalaninemia and 7-pterin excretion associated with mutations in 4a-hydroxy-tetrahydrobiopterin dehydratase/DCoH: analysis of enzyme activity in intestinal biopsies. Mol Genet Metab 2000 Jul 1
30 11056347 Induction of PCD in tamoxifen-resistant oestrogen receptor positive (ER+) advanced breast cancer after combined therapy with ER antisense oligonucleotides and vinorelbine-tartrate encapsulated in DRV liposomes Eur J Cancer 2000 Sep 3
31 11395380 Dimerization co-factor of hepatocyte nuclear factor 1/pterin-4alpha-carbinolamine dehydratase is necessary for pigmentation in Xenopus and overexpressed in primary human melanoma lesions. Am J Pathol 2001 Jun 3
32 11516724 Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation. Mutat Res 2001 Jun 27 10
33 11672088 Highly Regioselective Thioselenation of Acetylenes by Using a (PhS)(2)-(PhSe)(2) Binary System. J Org Chem 1998 Feb 6 1
34 11674089 Highly Selective Thioselenation of Vinylcyclopropanes with a (PhS)(2)-(PhSe)(2) Binary System and Its Application to Thiotelluration. J Org Chem 1999 Jan 8 5
35 12013526 The effect of betel nut extract on cell growth and prostaglandin endoperoxide synthase in human epidermoid carcinoma cells. Prostaglandins Other Lipid Mediat 2002 Apr 6
36 12377044 Substitution reactions of [Fe(4)S(4)Cl(4)](2-) with Bu(t)NC or Et(2)NCS(2)(-): trapping intermediates and detecting new pathways. Inorg Chem 2002 Oct 21 2
37 14607663 Effect of morphine and M-cholinoceptor blocking drugs on human sphincter of Oddi during choledochofiberscopy manometry. Hepatobiliary Pancreat Dis Int 2003 Feb 2
38 14634340 Nonsteroidal anti-inflammatory drugs and the induction of apoptosis in colon cells: evidence for PHS-dependent and PHS-independent mechanisms. Apoptosis 1999 Oct 2
39 14690392 Effect of pH on the thermal stability of potent roasty odorants, 3-mercapto-3-methylbutyl esters, in coffee drink. J Agric Food Chem 2003 Dec 31 1
40 15264930 Enzymolysis approach to compare cu availability from human milk and infant formulas. J Agric Food Chem 2004 Jul 28 1
41 16889893 Test method selection, validation against field data, and predictive modelling for impact evaluation of stabilised waste disposal. J Hazard Mater 2007 Mar 15 1
42 16935936 Specific interaction of the diastereomers 7(R)- and 7(S)-tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligo. FASEB J 2006 Oct 6
43 17002449 Reaction of thiometon and disulfoton with reduced sulfur species in simulated natural environment. J Agric Food Chem 2006 Oct 4 7
44 18044878 Rates of proton transfer to Fe-S-based clusters: comparison of clusters containing {MFe(mu(2)-S)(2)}n+ and {MFe(3)(mu(3)-S)(4)}n+ (M = Fe, Mo, or W) cores. Inorg Chem 2007 Dec 24 2
45 18540596 Binding nucleophiles to [Fe4Y4Cl4](2-) (Y = S or Se) can increase or suppress the rate of proton transfer to the cluster. Inorg Chem 2008 Jul 7 3
46 18627178 Microprocessing of liquid plugs for bio/chemical analyses. Anal Chem 2008 Aug 15 1
47 19234759 Disorders of biopterin metabolism. J Inherit Metab Dis 2009 Jun 1
48 20386803 Protonation and substitution reactions of [{WFe₃S₄Cl₃}₂(μ-L)₃]³⁻ (L = SEt or OMe): quantifying how metal content and spectator ligands individually affect reactivity. Dalton Trans 2010 May 21 6
49 21047120 Kinetic stability may determine the interaction dynamics of the bifunctional protein DCoH1, the dimerization cofactor of the transcription factor HNF-1α . Biochemistry 2010 Nov 30 1
50 21078384 Human prostaglandin H synthase (hPHS)-1- and hPHS-2-dependent bioactivation, oxidative macromolecular damage, and cytotoxicity of dopamine, its precursor, and its metabolites. Free Radic Biol Med 2011 Jan 15 16