dual specificity phosphatase 2 ; Homo sapiens






155 Article(s)
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51 15786005 Hypothermia-induced platelet aggregation: no effect of aprotinin (trasylol) but inhibition by eptifibatide (integrilin). Thorac Cardiovasc Surg 2005 Apr 1
52 15815879 Losartan and simvastatin inhibit platelet activation in hypertensive patients. J Thromb Thrombolysis 2004 Dec 1
53 15960075 Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro. Artif Cells Blood Substit Immobil Biotechnol 2005 1
54 16098428 Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug. J Am Coll Cardiol 2005 Aug 16 1
55 16288922 New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding. J Mol Biol 2005 Dec 9 3
56 16308186 The Retention Index Test Homburg (RTH-II): Response to clopidogrel and comparison with aggregometry and CD62P-expression. Platelets 2006 Feb 1
57 16321613 Anti-inflammatory effects of clopidogrel intake in renal transplant patients: effects on platelet-leukocyte interactions, platelet CD40 ligand expression, and proinflammatory biomarkers. Clin Pharmacol Ther 2005 Nov 1
58 16368298 Valsartan inhibits platelet activity at different doses in mild to moderate hypertensives: Valsartan Inhibits Platelets (VIP) trial. Am Heart J 2006 Jan 1
59 16386660 Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance. J Am Coll Cardiol 2006 Jan 3 1
60 16387079 Clinical study of Lipo PGE1-inhibiting platelet activation in acute rejection after kidney transplantation. Transplant Proc 2005 Dec 2
61 16409299 Bacitracin reveals a role for multiple thiol isomerases in platelet function. Br J Haematol 2006 Feb 1
62 16411409 Anti-thrombotic action of clopidogrel and P1(A1/A2) polymorphism of beta3 integrin in patients with coronary artery disease not being treated with aspirin. Thromb Haemost 2005 Dec 1
63 16497877 Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-kappaB inhibition and gene expression signature. Mol Pharmacol 2006 May 1
64 16551937 The effects of test temperature and storage temperature on platelet aggregation: a whole blood in vitro study. Anesth Analg 2006 Apr 1
65 16581111 Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel. Thromb Res 2007 1
66 16706985 Critical role of ADP interaction with P2Y12 receptor in the maintenance of alpha(IIb)beta3 activation: association with Rap1B activation. J Thromb Haemost 2006 Jun 2
67 16754711 Platelet inhibition with prasugrel (CS-747) compared with clopidogrel in patients undergoing coronary stenting: the subset from the JUMBO study. Postgrad Med J 2006 Jun 1
68 16837624 Prevention of platelet glycoprotein IIb/IIIa activation by 3,4-methylenedioxy-beta-nitrostyrene, a novel tyrosine kinase inhibitor. Mol Pharmacol 2006 Oct 1
69 17056832 The in vitro effects of a novel vascular protectant, AGI-1067, on platelet aggregation and major receptor expression in subjects with multiple risk factors for vascular disease. J Cardiovasc Pharmacol Ther 2006 Sep 1
70 17287623 Does heart failure etiology, New York Heart Association class, or ejection fraction affect the ability of clopidogrel to inhibit heightened platelet activity? Blood Coagul Fibrinolysis 2007 Mar 1
71 17554594 Abnormal PFA-100 closure time is associated with increased platelet aggregation in patients presenting with chest pain. J Thromb Thrombolysis 2008 Apr 2
72 17822662 Comparison of 1- and 2-week pantoprazole-based triple therapies in clarithromycin-sensitive and resistant cases. Eur J Intern Med 2007 Oct 3
73 17890860 Platelet activation during haemodialysis: comparison of cuprammonium rayon and polysulfone membranes. Blood Purif 2007 1
74 17892993 Effect of caffeine on platelet inhibition by clopidogrel in healthy subjects and patients with coronary artery disease. Am Heart J 2007 Oct 1
75 17956695 [Inhibition of L-arginine and cilostazol on activation of platelets in vitro]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2007 Oct 4
76 18088485 [Protective effects of DMSO on function of lyophilized human platelets]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2007 Dec 5
77 18201749 Tyr178 of beta3 is critical for alphaIIb maturation and macromolecular ligand binding to alphaIIbbeta3. Thromb Res 2008 1
78 18217151 Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement. Thromb Haemost 2008 Jan 2
79 18448152 The modified Je-Ho-Tang, Korean herbal medicine, inhibits whole-blood aggregation and platelet adhesion to collagen under flow. Thromb Res 2008 1
80 18569522 Does structural commonality of metal complex formation by PAC-1 (anticancer), DHBNH (anti-HIV), AHL (autoinducer), and UCS1025A (anticancer) denote mechanistic similarity? Signal transduction and medical aspects. J Recept Signal Transduct Res 2008 1
81 18942580 Fractionation of soluble microbial products (SMP) and soluble extracellular polymeric substances (EPS) from wastewater sludge. Environ Technol 2008 Oct 1
82 19513289 Cilostazol reduces PAC-1 expression on platelets in ischemic stroke. J Clin Neurol 2008 Dec 7
83 19803539 An economic evaluation of docetaxel and paclitaxel regimens in metastatic breast cancer in the UK. Pharmacoeconomics 2009 1
84 19874818 Disruption of actin cytoskeleton mediates loss of tensile stress induced early phenotypic modulation of vascular smooth muscle cells in organ culture. Exp Mol Pathol 2010 Feb 3
85 20356540 [The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia]. Zhonghua Yi Xue Za Zhi 2010 Jan 26 1
86 20369570 Effects of magnetic ion-exchange resin addition during coagulation on floc properties and membrane filtration. Water Environ Res 2010 Mar 2
87 20723301 [Influence of dipyridamole on expression of PAC-1 and CD62p in patients with malignant lymphoma]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2010 Aug 1
88 20946295 Comparison of two platelet activation markers using flow cytometry after in vitro shear stress exposure of whole human blood. Artif Organs 2011 Feb 2
89 21118406 Platelet activation in patients with the Raynaud phenomenon. Intern Med J 2012 May 2
90 21565849 Platelet reactivity and endothelial function in children of patients with early acute myocardial infarction. Eur Heart J 2011 Aug 1
91 21624644 Epoprostenol inhibits human platelet-leukocyte mixed conjugate and platelet microparticle formation in whole blood. Thromb Res 2011 Nov 1
92 21922132 Anti-angiogenic activity of cranberry proanthocyanidins and cytotoxic properties in ovarian cancer cells. Int J Oncol 2012 Jan 6
93 22720759 Exploration of the antiplatelet activity profile of betulinic acid on human platelets. J Agric Food Chem 2012 Jul 18 1
94 22883016 [Roles and mechanisms of E2F-1 and PAC1 in signaling oxidative stress-induced apoptosis of Saos-2 cells]. Zhonghua Yi Xue Za Zhi 2012 May 8 2
95 24030118 Increased PAC-1 expression among patients with multiple myeloma on concurrent thalidomide and warfarin. Blood Coagul Fibrinolysis 2013 Dec 3
96 24114959 Synthesis and biological evaluation of novel 4-(2-fluorophenoxy)-2-(1H-tetrazol-1-yl)pyridines bearing semicarbazone moieties as potent antitumor agents. Arch Pharm (Weinheim) 2013 Nov 1
97 24506417 Effects of riboflavin and ultraviolet light treatment on platelet thrombus formation on collagen via integrin αIIbβ3 activation. Transfusion 2014 Jul 2
98 24586940 PPARγ ligands decrease hydrostatic pressure-induced platelet aggregation and proinflammatory activity. PLoS One 2014 2
99 24616605 Platelet activity and sensitivity to agonists after exhaustive treadmill exercise. J Sports Sci Med 2003 Mar 2
100 24851838 Neuroprotection elicited by P2Y13 receptors against genotoxic stress by inducing DUSP2 expression and MAPK signaling recovery. Biochim Biophys Acta 2014 Sep 1