tropomyosin 1, alpha ; Mus musculus






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1 1332958 Thyrotropin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors. J Biol Chem 1992 Dec 5 2
2 2550403 The actions of calcitonin on the TM3 Leydig cell line and on rat Leydig cell-enriched cultures. J Androl 1989 Jul-Aug 3
3 3221870 Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells. Mol Cell Biol 1988 Sep 2
4 7728975 Tyrosine phosphorylation in mouse mammary hyperplasias. Carcinogenesis 1995 Apr 1
5 8120097 Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin. J Cell Biol 1994 Mar 2
6 8760295 Anti-oncogenic effects of tropomyosin: isoform specificity and importance of protein coding sequences. Oncogene 1996 Aug 1 1
7 8887371 Effect of gossypol on cultured TM3 Leydig and TM4 Sertoli cells: 31P and 23Na NMR study. NMR Biomed 1996 Apr 2
8 9388474 Molecular characterization of fetal alcohol syndrome using mRNA differential display. Biochem Biophys Res Commun 1997 Nov 17 2
9 10469615 Interactions of apoptosis, proliferation and host age in the regression of the mouse mammary preneoplasia, TM3, carrying an unusual mutation in p53. Carcinogenesis 1999 Sep 1
10 11360195 Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: Evidence for Rho kinase pathway. Oncogene 2001 Apr 19 2
11 11410806 Regulation of the growth of mouse Leydig cells by the inactive stereoisomer, 17alpha-estradiol: Lack of correlation between the elevated expression of ERalpha and difference in sensitivity to estradiol isomers. Oncol Rep 2001 Jul-Aug 1
12 12065096 Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. Cancer Lett 2002 Sep 26 5
13 12163104 Alcohol induces apoptosis in TM3 mouse Leydig cells via bax-dependent caspase-3 activation. Eur J Pharmacol 2002 Aug 2 2
14 12651873 Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. Hum Mol Genet 2003 Apr 1 2
15 14566825 Single amino acid substitutions in the transmembrane domains of breast cancer resistance protein (BCRP) alter cross resistance patterns in transfectants. Int J Cancer 2003 Dec 10 2
16 14581613 Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading. Proc Natl Acad Sci U S A 2003 Nov 11 1
17 14766940 Charged residue changes in the carboxy-terminus of alpha-tropomyosin alter mouse cardiac muscle contractility. J Physiol 2004 Apr 15 7
18 15040802 Stimulation of TM3 Leydig cell proliferation via GABA(A) receptors: a new role for testicular GABA. Reprod Biol Endocrinol 2004 Mar 24 8
19 15486021 Charged residue alterations in the inner-core domain and carboxy-terminus of alpha-tropomyosin differentially affect mouse cardiac muscle contractility. J Physiol 2004 Dec 15 3
20 15831280 Nicotine induces apoptosis in TM3 mouse Leydig cells. Fertil Steril 2005 Apr 2
21 16096341 Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+. J Physiol 2005 Oct 15 3
22 16276116 Insights into GABA receptor signalling in TM3 Leydig cells. Neuroendocrinology 2005 4
23 16520747 Mutations of L293 in transmembrane two of the mouse 5-hydroxytryptamine3A receptor alter gating and alcohol modulatory actions. Br J Pharmacol 2006 May 1
24 16752004 Cox7a2 mediates steroidogenesis in TM3 mouse Leydig cells. Asian J Androl 2006 Sep 5
25 17553632 Cytoprotective effect of Panax ginseng on gallic acid-induced toxicity in TM3 mouse Leydig cells. Fitoterapia 2007 Dec 3
26 17647204 Prediction of the 3D structure of FMRF-amide neuropeptides bound to the mouse MrgC11 GPCR and experimental validation. Chembiochem 2007 Sep 3 1
27 17899337 Synthesized esters of ferulic acid induce release of cytochrome c from rat testes mitochondria. J Bioenerg Biomembr 2008 Feb 2
28 18486176 Interactions of methoxyacetic acid with androgen receptor. Toxicol Appl Pharmacol 2009 Jul 15 1
29 18785754 Functional and structural characterization of 2B viroporin membranolytic domains. Biochemistry 2008 Oct 7 2
30 18930903 Hypoxia-inducible factor-1alpha is constitutively expressed in murine Leydig cells and regulates 3beta-hydroxysteroid dehydrogenase type 1 promoter activity. J Androl 2009 Mar-Apr 1
31 19129676 Suppressive action of pituitary adenylate cyclase activating polypeptide (PACAP) on proliferation of immature mouse Leydig cell line TM3 cells. Biomed Res 2008 Dec 2
32 19429821 An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. Am J Physiol Heart Circ Physiol 2009 Jul 1
33 19530183 A cytoskeletal tropomyosin can compromise the structural integrity of skeletal muscle. Cell Motil Cytoskeleton 2009 Sep 1
34 19571123 Location of the beta 4 transmembrane helices in the BK potassium channel. J Neurosci 2009 Jul 1 3
35 19858190 Conformational changes associated with proton-dependent gating of ASIC1a. J Biol Chem 2009 Dec 25 1
36 20803058 Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity. J Muscle Res Cell Motil 2010 Sep 1
37 21056571 Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. J Mol Cell Cardiol 2011 Jan 1
38 21548202 [P70S6K is involved in the inhibition of testosterone production in TM3 mouse Leydig cells overexpressing Cox7a2]. Zhonghua Nan Ke Xue 2011 Apr 1
39 21743000 Effects of nicotine administration in a mouse model of familial hypertrophic cardiomyopathy, α-tropomyosin D175N. Am J Physiol Heart Circ Physiol 2011 Oct 1
40 22711419 Gene expression analysis of toxicological pathways in TM3 leydig cell lines treated with Ethane dimethanesulfonate. J Biochem Mol Toxicol 2012 Jun 2
41 23065098 Histone H3 lysine 27 and 9 hypermethylation within the Bad promoter region mediates 5-Aza-2'-deoxycytidine-induced Leydig cell apoptosis: implications of 5-Aza-2'-deoxycytidine toxicity to male reproduction. Apoptosis 2013 Jan 4
42 23148217 Tropomyosin dephosphorylation results in compensated cardiac hypertrophy. J Biol Chem 2012 Dec 28 2
43 23200789 Identification of blocker binding site in mouse TRESK by molecular modeling and mutational studies. Biochim Biophys Acta 2013 Mar 2
44 23609439 Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. J Biol Chem 2013 Jun 7 5
45 23800848 Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiol Genomics 2013 Sep 3 2
46 23930009 Anti-microorganism, anti-tumor, and immune activities of a novel polysaccharide isolated from Tricholoma matsutake. Pharmacogn Mag 2013 Jul 3
47 24387279 Reduced testosterone production in TM3 Leydig cells treated with Aspalathus linearis (Rooibos) or Camellia sinensis (tea). Andrologia 2015 Feb 1
48 24585742 Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circ Cardiovasc Genet 2014 Apr 1
49 24810894 Epigenetic regulation of sox30 is associated with testis development in mice. PLoS One 2014 1
50 25733828 Differential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells. Int J Nanomedicine 2015 2