phosphogluconate dehydrogenase ; Homo sapiens






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1 554655 [Aspects of the decrease of some enzyme activities in erythrocytes of subjects with beta-thalassemia]. Boll Soc Ital Biol Sper 1979 Apr 30 1
2 623919 [The determination of the red cell isoenzymes 6-phosphogluconate dehydrogenase (E.C.1.1.1.44) and acid phosphatase (E.C.3.1.3.2) by means of agarosegel thinlayer electrophoresis (author's transl)]. Blut 1978 Jan 20 1
3 1666816 Clinical utility of fractionating erythrocytes into "Percoll" density gradients. Adv Exp Med Biol 1991 2
4 1870419 Triiodothyronine (T3)-associated upregulation and downregulation of nuclear T3 binding in the human fibroblast cell (MRC-5)--stimulation of malic enzyme, glucose-6-phosphate-dehydrogenase, and 6-phosphogluconate-dehydrogenase by insulin, but not by T3. Metabolism 1991 Jul 6
5 2394215 Analysis of 6-phosphogluconate dehydrogenase isozymes by polyacrylamide gel isoelectric focusing. Electrophoresis 1990 Jun 3
6 3770750 Polymorphism of 6-PGD in South Korea: a new genetic variant 6-PGD Korea. Hum Genet 1986 Oct 1
7 4024601 [Erythrocyte enzymes in chronic kidney failure]. Vutr Boles 1985 3
8 4647721 Comments on the determination of isoenzyme polymorphism (ADA, AK, 6-PGD, PGM) by cellulose acetate electrophoresis. Humangenetik 1972 1
9 6234985 Inhibition of 6-phosphogluconate dehydrogenase by glucose 1,6-diphosphate in human normal and malignant colon extracts. Cancer Lett 1984 Jun 7
10 6860590 Inhibition of the pentose phosphate shunt by 2,3-diphosphoglycerate in erythrocyte pyruvate kinase deficiency. Br J Haematol 1983 Jul 7
11 7082864 Separate detection of glucose-6-phosphate dehydrogenase from 6-phosphogluconate dehydrogenase by DEAE-paper chromatography. Blut 1982 Jul 3
12 7107799 Automated purification of human erythrocytic 6-phosphogluconate dehydrogenase. J Chromatogr 1982 Jul 2 6
13 7639506 Inactivation and cleavage of liver 6-P-gluconate dehydrogenase during irradiation in the presence of vanadate. Arch Biochem Biophys 1995 Aug 1 1
14 7737089 Electrophoretic conditions for high resolution citrus isozymes in polyacrylamide gel electrophoresis. Electrophoresis 1995 Jan 1
15 15553090 Functional constraints of 6-phosphogluconate dehydrogenase (6-PGD) based on sequence and structural information. J Mol Evol 2004 Sep 6
16 15624330 [Study on red cell enzymes and isoenzymes in patients with leukemia and myelodysplastic syndromes]. Zhonghua Xue Ye Xue Za Zhi 1997 Jul 1
17 21188075 Enzymatic and mRNA Transcript Response of Ovine 6-Phosphogluconate Dehydrogenase (6PGD) in Respect to Different Milk Yield. Biochem Res Int 2010 3
18 22677172 Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence. FEBS Lett 2012 Jul 30 5
19 24018234 One-step purification of soluble recombinant human 6-phosphogluconate dehydrogenase from Escherichia coli. Protein Expr Purif 2013 Nov 5
20 25042803 Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth. Mol Cell 2014 Aug 21 9
21 25130191 Investigation of the effects of some phenolic compounds on the activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from human erythrocytes. J Biochem Mol Toxicol 2014 Nov 3
22 27270429 Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. Oncogene 2017 Jan 12 3
23 28713273 Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung Cancer. Front Pharmacol 2017 11
24 28848047 Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions. J Biol Chem 2017 Oct 13 5
25 28978059 Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming. Oncotarget 2017 Sep 15 8
26 29340974 Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation. Clin Transl Oncol 2018 Sep 2
27 29534964 Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming. Biochem Biophys Res Commun 2018 Apr 15 13
28 30625329 Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Rep 2019 Jan 8 2
29 30824700 Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance. Nat Commun 2019 Mar 1 15
30 30841449 6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming. Biomed Pharmacother 2019 Mar 5
31 31557707 Inhibition effects of some antidepressant drugs on pentose phosphate pathway enzymes. Environ Toxicol Pharmacol 2019 Nov 15
32 31586547 γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell 2019 Dec 19 2
33 31848848 Di(2-ethylhexyl) phthalate inhibits glutathione regeneration and dehydrogenases of the pentose phosphate pathway on human colon carcinoma cells. Cell Stress Chaperones 2020 Jan 4
34 32336239 The positive feedback loop between Nrf2 and phosphogluconate dehydrogenase stimulates proliferation and clonogenicity of human hepatoma cells. Free Radic Res 2020 Dec 1
35 32719331 HIF-1α regulates cellular metabolism, and Imatinib resistance by targeting phosphogluconate dehydrogenase in gastrointestinal stromal tumors. Cell Death Dis 2020 Jul 27 1
36 32792504 Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis. Nat Commun 2020 Aug 13 6
37 32801914 Discovery of Ebselen as an Inhibitor of 6PGD for Suppressing Tumor Growth. Cancer Manag Res 2020 8
38 32829780 6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming. Am J Med Sci 2020 Sep 6
39 33438819 The effect of brimonidine and proparacaine on metabolic enzymes: Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase. Biotechnol Appl Biochem 2022 Feb 4
40 33498665 Oxidative Pentose Phosphate Pathway Enzyme 6-Phosphogluconate Dehydrogenase Plays a Key Role in Breast Cancer Metabolism. Biology (Basel) 2021 Jan 23 3
41 33817181 1-Hydroxy-8-methoxy-anthraquinon Reverses Cisplatin Resistance by Inhibiting 6PGD in Cancer Cells. Open Life Sci 2019 Jan 11
42 34382934 A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth. Elife 2021 Aug 12 1
43 34765544 Oncogenic Integration of Nucleotide Metabolism <i>via</i> Fatty Acid Synthase in Non-Hodgkin Lymphoma. Front Oncol 2021 6
44 35075686 Methyl benzoate derivatives as inhibitors of pentose phosphate pathway, which promotes cancer progression and drug resistance: An in silico study supported by in vitro results. Biotechnol Appl Biochem 2022 Jan 24 3