protein kinase C, zeta ; Mus musculus






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1 8765021 Association of phosphatidylinositol 3 kinase to protein kinase C zeta during interleukin-2 stimulation. Eur J Immunol 1996 Aug 4
2 9074951 Activation of phorbol ester responsive form of protein kinase C zeta in association with Ca(2+)-induced differentiation of primary cultured mouse epidermal cells. Jpn J Pharmacol 1997 Feb 3
3 9268711 Phorbol ester effects in atypical protein kinase C zeta overexpressing NIH3T3 cells: possible evidence for crosstalk between protein kinase C isoforms. Biochem Biophys Res Commun 1997 Aug 18 6
4 11063744 Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin. J Biol Chem 2001 Feb 2 2
5 11080619 Phosphatidylinositol-3-kinase activation and atypical protein kinase C zeta phosphorylation characterize the DMSO signalling in erythroleukemia cells. Cell Signal 2000 Oct 1
6 12469195 Engagement of PI-3-kinase mediated protein kinase C zeta activation in protecting Friend cells from ionizing radiation-induced apoptosis. Int J Oncol 2003 Jan 1
7 15723051 PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1. Nat Cell Biol 2005 Mar 1
8 15891936 Molecular targeting of pancreatic disorders. World J Surg 2005 Mar 1
9 17335965 The Par6alpha/aPKC complex regulates Akt1 activity by phosphorylating Thr34 in the PH-domain. Mol Cell Endocrinol 2007 Mar 30 2
10 17983354 Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide. Biochem J 2008 Mar 1 4
11 18202124 Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling. Endocrinology 2008 May 1
12 19129633 KIBRA Co-localizes with protein kinase Mzeta (PKMzeta) in the mouse hippocampus. Biosci Biotechnol Biochem 2009 Jan 2
13 19424853 Calorie restriction initiated at a young age activates the Akt/PKC zeta/lambda-Glut4 pathway in rat white adipose tissue in an insulin-independent manner. Age (Dordr) 2008 Dec 3
14 19887597 AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC. Am J Physiol Endocrinol Metab 2010 Feb 13
15 20236512 RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones. Mol Cancer 2010 Mar 17 1
16 20407013 Activation by tyrosine phosphorylation as a prerequisite for protein kinase Cζ to mediate epidermal growth factor receptor signaling to ERK. Mol Cancer Res 2010 May 8
17 22148072 Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells. Diabetes 2012 Jan 1
18 22170052 Up-regulation of ATP binding cassette transporter A1 expression by very low density lipoprotein receptor and apolipoprotein E receptor 2. J Biol Chem 2012 Feb 3 1
19 22232556 Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts. J Biol Chem 2012 Mar 2 1
20 22474074 Small interfering RNA-mediated knockdown of protein kinase C zeta attenuates domoic acid-induced cognitive deficits in mice. Toxicol Sci 2012 Jul 6
21 23905844 Deletion of Prkcz increases intermittent ethanol consumption in mice. Alcohol Clin Exp Res 2014 Jan 6
22 24997360 Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst. Dev Biol 2014 Oct 1 1
23 25296984 Abi3bp regulates cardiac progenitor cell proliferation and differentiation. Circ Res 2014 Dec 5 1
24 25395359 Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation. J Lipid Res 2015 Jan 3
25 25566006 Methamphetamine-induced short-term increase and long-term decrease in spatial working memory affects protein Kinase M zeta (PKMζ), dopamine, and glutamate receptors. Front Behav Neurosci 2014 1
26 25625560 Melatonin improves experimental colitis with sleep deprivation. Int J Mol Med 2015 Apr 1
27 26288989 Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle via K(Ca) 1.1 upregulation. Aging Cell 2015 Dec 1
28 26386696 BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans. Metabolism 2015 Nov 1
29 26780350 The memory-enhancing effect of erucic acid on scopolamine-induced cognitive impairment in mice. Pharmacol Biochem Behav 2016 Mar 5
30 26976654 Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS)1(-/-), and IRS2(-/-) male mice fed a high-fat diet. J Steroid Biochem Mol Biol 2016 May 1
31 27328732 Eritoran Suppresses Colon Cancer by Altering a Functional Balance in Toll-like Receptors That Bind Lipopolysaccharide. Cancer Res 2016 Aug 15 5
32 27486964 Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury. Am J Respir Cell Mol Biol 2016 Dec 3
33 28743803 The glucocorticoid-Angptl4-ceramide axis induces insulin resistance through PP2A and PKCζ. Sci Signal 2017 Jul 25 1
34 29988567 Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1. FEBS Open Bio 2018 Jul 3
35 30201979 Ectopic expression of aPKC-mediated phosphorylation in p300 modulates hippocampal neurogenesis, CREB binding and fear memory differently with age. Sci Rep 2018 Sep 10 2
36 30914305 Mechanisms underpinning AMP-activated protein kinase-related effects on behavior and hippocampal neurogenesis in an animal model of depression. Neuropharmacology 2019 May 15 2
37 31053639 An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice. J Biol Chem 2019 Jun 7 7
38 31620609 Telmisartan increases hepatic glucose production via protein kinase C ζ-dependent insulin receptor substrate-1 phosphorylation in HepG2 cells and mouse liver. Yeungnam Univ J Med 2019 Jan 8
39 32483456 Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease. Theranostics 2020 1
40 32800853 Activation of AMPK/aPKCζ/CREB pathway by metformin is associated with upregulation of GDNF and dopamine. Biochem Pharmacol 2020 Oct 3
41 32937657 Brain α-Tocopherol Concentration and Stereoisomer Profile Alter Hippocampal Gene Expression in Weanling Mice. J Nutr 2020 Dec 10 1
42 33281604 Scabronine G Methyl Ester Improves Memory-Related Behavior and Enhances Hippocampal Cell Proliferation and Long-Term Potentiation via the BDNF-CREB Pathway in Olfactory Bulbectomized Mice. Front Pharmacol 2020 2