phorbol-12-myristate-13-acetate-induced protein 1 ; Mus musculus






28 Article(s)
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1 10807576 Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000 May 12 1
2 12968018 Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress. J Biol Chem 2003 Nov 28 1
3 15561702 Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine. J Biol Chem 2005 Feb 18 1
4 16928686 Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa. J Biol Chem 2006 Oct 20 1
5 18056701 Paraquat neurotoxicity is mediated by a Bak-dependent mechanism. J Biol Chem 2008 Feb 8 1
6 19237507 Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation. FASEB J 2009 Jul 1
7 19826054 The cell death-inducing activity of the peptide containing Noxa mitochondrial-targeting domain is associated with calcium release. Cancer Res 2009 Nov 1 1
8 21468686 Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737. Cell Oncol (Dordr) 2011 Aug 2
9 21737676 The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration. Mol Biol Cell 2011 Sep 1
10 23213401 ABT-737 synergizes with Bortezomib to kill melanoma cells. Biol Open 2012 Feb 15 3
11 23593480 Oppositional regulation of Noxa by JNK1 and JNK2 during apoptosis induced by proteasomal inhibitors. PLoS One 2013 1
12 23605481 AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts. Apoptosis 2013 Aug 2
13 23859824 C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis. Mol Cell Neurosci 2013 Sep 2
14 24608793 Zebrafish Noxa promotes mitosis in early embryonic development and regulates apoptosis in subsequent embryogenesis. Cell Death Differ 2014 Jun 1
15 25124553 Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins. Cell Death Differ 2015 Jan 1
16 25542456 Pifithrin-α ameliorates resveratrol-induced two-cell block in mouse preimplantation embryos in vitro. Theriogenology 2015 Mar 15 1
17 25546121 Establishment of a rapid drug screening system based on embryonic stem cells. Environ Toxicol Pharmacol 2015 Jan 1
18 26181197 Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin. Cell Death Dis 2015 Jul 16 1
19 27862899 Pro-apoptotic Noxa is involved in ablative focal irradiation-induced lung injury. J Cell Mol Med 2017 Apr 1
20 28079889 Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice. Cell Death Dis 2017 Jan 12 1
21 29228353 The Roles of P53 and Its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis-Stage Mouse Embryos. Toxicol Sci 2018 Apr 1 1
22 30017199 ABT-199-mediated inhibition of Bcl-2 as a potential therapeutic strategy for nasopharyngeal carcinoma. Biochem Biophys Res Commun 2018 Sep 10 3
23 30445933 Homoharringtonine interacts synergistically with bortezomib in NHL cells through MCL-1 and NOXA-dependent mechanisms. BMC Cancer 2018 Nov 16 4
24 31371419 Combined inhibition of MDM2 and BCR-ABL1 tyrosine kinase targets chronic myeloid leukemia stem/progenitor cells in a murine model. Haematologica 2020 May 1
25 31580946 The vanillin derivative VND3207 protects intestine against radiation injury by modulating p53/NOXA signaling pathway and restoring the balance of gut microbiota. Free Radic Biol Med 2019 Dec 1
26 33202325 Effect of pristimerin on apoptosis through activation of ROS/ endoplasmic reticulum (ER) stress-mediated noxa in colorectal cancer. Phytomedicine 2021 Jan 3
27 34332177 Autophagic degradation of NOXA underlies stromal cell-mediated resistance to proteasome inhibitors in mantle cell lymphoma. Leuk Res 2021 Dec 4
28 34822928 The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism. Cancer Lett 2022 Feb 1 6