Protein Name phorbol-12-myristate-13-acetate-induced protein 1
Organism Mus musculus
Gene ID 58801
Gene Symbol

Pmaip1

UniProt Q9JM54 (APR_MOUSE)
Relationships Total Number of functionally related compound(s) : 30
Total Number of Articles : 28
Description

phorbol-12-myristate-13-acetate-induced protein 1

Gene Summary

Involved in several processes, including apoptotic signaling pathway; negative regulation of mitochondrial membrane potential; and positive regulation of DNA damage response, signal transduction by p53 class mediator. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; positive regulation of apoptotic process; and positive regulation of establishment of protein localization to mitochondrion. Located in mitochondrion. Is expressed in several structures, including brain; genitourinary system; immune system; limb; and liver. Orthologous to human PMAIP1 (phorbol-12-myristate-13-acetate-induced protein 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • phorbol-12-myristate-13-acetate-induced protein 1
  • protein Noxa
  • Noxa
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Properties