growth hormone secretagogue receptor ; Mus musculus






181 Article(s)
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1 15070777 Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A 2004 Mar 30 1
2 15591499 Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin. Gut 2005 Jan 3
3 15843418 Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro. Gut 2005 Aug 2
4 16115456 [Ghrelin: a striking example of neuroendocrine peptide pleiotropy]. Med Sci (Paris) 2005 Aug-Sep 2
5 16210421 Effect of chronic hyperghrelinemia on ingestive action of ghrelin. Am J Physiol Regul Integr Comp Physiol 2006 Mar 1
6 16244497 Expression analysis of hypothalamic and pituitary components of the growth hormone axis in fasted and streptozotocin-treated neuropeptide Y (NPY)-intact (NPY+/+) and NPY-knockout (NPY-/-) mice. Neuroendocrinology 2005 1
7 16322795 Absence of ghrelin protects against early-onset obesity. J Clin Invest 2005 Dec 2
8 16530883 [Trp3, Arg5]-ghrelin(1-5) stimulates growth hormone secretion and food intake via growth hormone secretagogue (GHS) receptor. Peptides 2006 Jul 1
9 16601073 Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Mol Endocrinol 2006 Aug 3
10 16685441 Effects of ghrelin on anorexia in tumor-bearing mice with eicosanoid-related cachexia. Int J Oncol 2006 Jun 2
11 16825606 Evidence that endogenous SST inhibits ACTH and ghrelin expression by independent pathways. Am J Physiol Endocrinol Metab 2006 Aug 2
12 17130496 Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance. Diabetes 2006 Dec 1
13 17407492 Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addict Biol 2007 Mar 3
14 17622734 Heterogeneity of ghrelin/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin/GHS receptors. Neuroendocrinology 2007 1
15 17656463 Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss. Endocrinology 2007 Nov 1
16 17898534 Central and peripheral roles of ghrelin on glucose homeostasis. Neuroendocrinology 2007 1
17 18056963 Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging. Ann N Y Acad Sci 2007 Nov 5
18 18202139 The gastrointestinal hormone ghrelin modulates inhibitory neurotransmission in deep laminae of mouse spinal cord dorsal horn. Endocrinology 2008 May 2
19 18450953 Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation. Endocrinology 2008 Aug 1
20 18453014 Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice. Regul Pept 2008 Oct 9 4
21 18577498 Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra. Exp Neurol 2008 Aug 2
22 19252061 Enhanced gastrointestinal motility with orally active ghrelin receptor agonists. J Pharmacol Exp Ther 2009 Jun 1
23 19564604 Requirement of central ghrelin signaling for alcohol reward. Proc Natl Acad Sci U S A 2009 Jul 7 5
24 19608205 Ghrelin and obestatin modulate early atherogenic processes on cells: enhancement of monocyte adhesion and oxidized low-density lipoprotein binding. Metabolism 2009 Nov 1
25 20477752 Ghrelin increases intake of rewarding food in rodents. Addict Biol 2010 Jul 1
26 20559820 Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference. Psychopharmacology (Berl) 2010 Sep 9
27 20586761 Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin-containing neurons. Alcohol Clin Exp Res 2010 Sep 1 1
28 20597975 Altered metabolic and neurochemical responses to chronic unpredictable stressors in ghrelin receptor-deficient mice. Eur J Neurosci 2010 Aug 1
29 20620030 Acute and chronic suppression of the central ghrelin signaling system reveals a role in food anticipatory activity. Eur Neuropsychopharmacol 2011 May 1
30 20668691 Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice. PLoS One 2010 Jul 26 2
31 20856820 Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants. PLoS One 2010 Sep 14 5
32 21054685 Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice. Addict Biol 2011 Jul 2
33 21145690 The alcohol-induced locomotor stimulation and accumbal dopamine release is suppressed in ghrelin knockout mice. Alcohol 2011 Jun 5
34 21211044 Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps. BMC Physiol 2011 Jan 6 9
35 21309944 Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats. Addict Biol 2012 Jan 10
36 21310553 Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice. Drug Alcohol Depend 2011 Sep 1 18
37 21392542 Expression of the gene encoding the ghrelin receptor in rats selected for differential alcohol preference. Behav Brain Res 2011 Aug 1 3
38 21691079 Activation of growth hormone secretagogue type 1a receptor inhibits T-type Ca2+ channel currents through pertussis toxin-sensitive novel protein kinase C pathway in mouse spermatogenic cells. Cell Physiol Biochem 2011 1
39 21719535 Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells. Mol Endocrinol 2011 Sep 1
40 21777303 Ghrelin and obestatin modulate growth hormone-releasing hormone release and synaptic inputs onto growth hormone-releasing hormone neurons. Eur J Neurosci 2011 Sep 1
41 21778696 GSK1614343, a novel ghrelin receptor antagonist, produces an unexpected increase of food intake and body weight in rodents and dogs. Neuroendocrinology 2011 1
42 21781995 Physiological roles revealed by ghrelin and ghrelin receptor deficient mice. Peptides 2011 Nov 1
43 21892647 Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task. Psychopharmacology (Berl) 2012 Mar 1
44 21895961 Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues. Aging Cell 2011 Dec 1
45 21963822 Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin. Regul Pept 2012 Jan 10 3
46 22284186 Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism. Neuron 2012 Jan 26 7
47 22363652 Ghrelin indirectly activates hypophysiotropic CRF neurons in rodents. PLoS One 2012 2
48 22391948 Ghrelin contributes to derangements of glucose metabolism induced by rapamycin in mice. Diabetologia 2012 Jun 2
49 22484009 Growth hormone secretagogue receptor (GHS-R1a) knockout mice exhibit improved spatial memory and deficits in contextual memory. Behav Brain Res 2012 Jun 15 2
50 22493744 Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. PLoS One 2012 4