Protein Name growth hormone secretagogue receptor
Organism Mus musculus
Gene ID 208188
Gene Symbol

Ghsr

UniProt Q99P50 (GHSR_MOUSE), Q0VBE5 (Q0VBE5_MOUSE)
Relationships Total Number of functionally related compound(s) : 119
Total Number of Articles : 181
Description

growth hormone secretagogue receptor

Gene Summary

Predicted to enable G protein-coupled receptor activity; identical protein binding activity; and peptide hormone binding activity. Involved in adult feeding behavior and positive regulation of appetite. Acts upstream of or within several processes, including cellular response to insulin stimulus; growth hormone secretion; and positive regulation of insulin-like growth factor receptor signaling pathway. Predicted to be located in cell surface; membrane raft; and neuron projection. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; and trachea. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • growth hormone secretagogue receptor type 1
  • G-protein coupled receptor
  • GH-releasing peptide receptor
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Properties