Pub. Date : 2009 Jul 7
PMID : 19564604
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | By contrast, central or peripheral administration of ghrelin receptor (GHS-R1A) antagonists suppressed alcohol intake in this model. | Alcohols | growth hormone secretagogue receptor | Mus musculus |
2 | By contrast, central or peripheral administration of ghrelin receptor (GHS-R1A) antagonists suppressed alcohol intake in this model. | Alcohols | growth hormone secretagogue receptor | Mus musculus |
3 | Alcohol-induced locomotor stimulation, accumbal dopamine release and conditioned place preference were abolished in models of suppressed central ghrelin signaling: GHS-R1A knockout mice and mice treated with 2 different GHS-R1A antagonists. | Alcohols | growth hormone secretagogue receptor | Mus musculus |
4 | Alcohol-induced locomotor stimulation, accumbal dopamine release and conditioned place preference were abolished in models of suppressed central ghrelin signaling: GHS-R1A knockout mice and mice treated with 2 different GHS-R1A antagonists. | Alcohols | growth hormone secretagogue receptor | Mus musculus |
5 | Thus, central ghrelin signaling, via GHS-R1A, not only stimulates the reward system, but is also required for stimulation of that system by alcohol. | Alcohols | growth hormone secretagogue receptor | Mus musculus |