cyclin D2 ; Homo sapiens






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1 7529333 Expression of cyclin D2 in Epstein-Barr virus-positive Burkitt's lymphoma cell lines is related to methylation status of the gene. J Virol 1995 Feb 2
2 7742549 Overexpression of cyclin D2 in chronic B-cell malignancies. Blood 1995 May 15 2
3 7806527 Differential requirements for interleukin-2 distinguish the expression and activity of the cyclin-dependent kinases Cdk4 and Cdk2 in human T cells. J Biol Chem 1994 Dec 30 2
4 8033212 Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 1994 Jul 15 1
5 8242751 The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993 Nov 19 1
6 8268127 IL-2-dependent induction of G1 cyclins in primary T cells is not blocked by rapamycin or cyclosporin A. Int Immunol 1993 Oct 2
7 8382693 Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes. J Biol Chem 1993 Feb 25 2
8 8710379 Tyrosine kinase inhibitor herbimycin A reduces the stability of cyclin-dependent kinase Cdk6 protein in T-cells. Oncogene 1996 Jul 18 1
9 8945475 Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis. Nature 1996 Dec 5 1
10 9655257 Interaction of retinoblastoma protein and D cyclins during cell-growth inhibition by hexamethylenebisacetamide in TM2H mouse epithelial cells. Mol Carcinog 1998 Jun 1
11 10359571 Early induction of cyclin D2 expression in phorbol ester-responsive B-1 lymphocytes. J Exp Med 1999 Jun 7 10
12 10378783 Butyrolactone I induces cyclin B1 and causes G2/M arrest and skipping of mitosis in human prostate cell lines. Cancer Lett 1999 Apr 26 1
13 10930570 The mitogenic signaling pathway for fibroblast growth factor-2 involves the tyrosine phosphorylation of cyclin D2 in MCF-7 human breast cancer cells. FEBS Lett 2000 Aug 4 4
14 11236942 The bone marrow stromal microenvironment influences myeloma therapeutic response in vitro. Leukemia 2001 Feb 1
15 11350919 Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells. Clin Cancer Res 2001 May 1
16 11823472 Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes. J Biol Chem 2002 Apr 5 1
17 12375011 Cyclin D2 expression in familial and sporadic breast cancer. Oncol Rep 2002 Nov-Dec 1
18 12483537 Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation. Oncogene 2002 Dec 12 1
19 12517729 Differential modulation of interleukin-2-and interleukin-4-mediated early activation of normal human B lymphocytes by the caspase inhibitor zVAD-fmk. Eur Cytokine Netw 2002 Oct-Dec 1
20 12649303 Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells. J Pharmacol Exp Ther 2003 Jun 4
21 12663518 Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis 2003 Mar 1
22 12684418 Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues. Clin Cancer Res 2003 Apr 1
23 12771922 Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer. Br J Cancer 2003 May 19 3
24 12878861 Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells. Cancer Biol Ther 2003 May-Jun 2
25 12884287 4-1BB enhances CD8+ T cell expansion by regulating cell cycle progression through changes in expression of cyclins D and E and cyclin-dependent kinase inhibitor p27kip1. Eur J Immunol 2003 Aug 1
26 12921950 Relationship between cyclin D1 and p21(Waf1/Cip1) during differentiation of human myeloid leukemia cell lines. Leuk Res 2003 Dec 1
27 14612939 Promoter methylation of cyclin D2 gene in gastric carcinoma. Int J Oncol 2003 Dec 2
28 14660677 A permissive role for phosphatidylinositol 3-kinase in the Stat5-mediated expression of cyclin D2 by the interleukin-2 receptor. J Biol Chem 2004 Feb 13 1
29 14975735 Heme controls the expression of cell cycle regulators and cell growth in HeLa cells. Biochem Biophys Res Commun 2004 Mar 12 1
30 14980522 Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells. Exp Cell Res 2004 Mar 10 1
31 15070696 Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone. Blood 2004 Apr 15 1
32 15103748 Sensitivity of B-cell chronic lymphocytic leukemia to Rituximab and Campath-1H and correlation with the expression of cell cycle regulatory proteins. Croat Med J 2004 Apr 1
33 15116089 Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins. Oncogene 2004 Apr 29 1
34 15169570 The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells. Retrovirology 2004 Apr 13 1
35 15245432 17beta-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression. J Invest Dermatol 2004 Aug 9
36 15328171 Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumors. Clin Cancer Res 2004 Aug 15 1
37 15509806 FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism. Mol Cell Biol 2004 Nov 2
38 15587392 The effect of sodium butyrate in combination with ATRA on the proliferation/differentiation of SKM-1. J Huazhong Univ Sci Technolog Med Sci 2004 3
39 15870436 Constitutively active K-cyclin/cdk6 kinase in Kaposi sarcoma-associated herpesvirus-infected cells. J Natl Cancer Inst 2005 May 4 1
40 16024653 Retinoid targeting of different D-type cyclins through distinct chemopreventive mechanisms. Cancer Res 2005 Jul 15 1
41 16174765 Efficient intervention of growth and infiltration of primary adult T-cell leukemia cells by an HIV protease inhibitor, ritonavir. Blood 2006 Jan 15 1
42 16182291 The polycomb group gene product Mel-18 interacts with cyclin D2 and modulates its activity. FEBS Lett 2005 Oct 10 1
43 16632470 Activated Jak2 with the V617F point mutation promotes G1/S phase transition. J Biol Chem 2006 Jun 30 1
44 16858664 Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21. Planta Med 2006 Aug 1
45 17343197 [The effect of cyclin D2 shRNA on the proliferation and apoptosis of LP-1 cell]. Zhonghua Xue Ye Xue Za Zhi 2006 Oct 1
46 17510244 Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinase-dependent pathway in rat granulosa cells. Endocrinology 2007 Aug 1
47 17634406 Acteoside inhibits human promyelocytic HL-60 leukemia cell proliferation via inducing cell cycle arrest at G0/G1 phase and differentiation into monocyte. Carcinogenesis 2007 Sep 1
48 18097580 Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A. Oncol Rep 2008 Jan 1
49 18431519 Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity. J Clin Invest 2008 May 4
50 18474441 Induction of G1 phase arrest and apoptosis in MDA-MB-231 breast cancer cells by troglitazone, a synthetic peroxisome proliferator-activated receptor gamma (PPARgamma) ligand. Cell Biol Int 2008 Aug 1