Title : Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.

Pub. Date : 2004 Apr 15

PMID : 15070696






1 Functional Relationships(s)
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1 By using a panel of MM cell lines we showed that rapamycin induced G0/G1 arrest, an effect being associated with an increase of the cyclin-dependent kinase inhibitor p27 and a decrease of cyclins D2 and D3. Sirolimus cyclin D2 Homo sapiens