SMAD family member 2 ; Rattus norvegicus






305 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 9812998 Smad2 overexpression enhances Smad4 gene expression and suppresses CBFA1 gene expression in osteoblastic osteosarcoma ROS17/2.8 cells and primary rat calvaria cells. J Biol Chem 1998 Nov 20 1
2 10382592 Involvement of Smad proteins in the differentiation of pancreatic AR42J cells induced by activin A. Diabetologia 1999 Jun 1
3 10966845 Dexamethasone inhibition of TGF beta-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes. Osteoarthritis Cartilage 2000 Sep 1
4 11074605 Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats. Mol Carcinog 2000 Oct 2
5 11087260 Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro. Am J Physiol Heart Circ Physiol 2000 Dec 2
6 11173539 Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats. Jpn J Cancer Res 2001 Jan 5
7 12039975 Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol 2002 Jun 1
8 12154106 N-acetyl-Ser-Asp-Lys-Pro inhibits phosphorylation of Smad2 in cardiac fibroblasts. Hypertension 2002 Aug 1
9 12668667 SMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cells. J Biol Chem 2003 May 30 1
10 12875981 Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction. Am J Pathol 2003 Aug 1
11 14512875 p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts. Hepatology 2003 Oct 1
12 14568256 A blocking peptide for transforming growth factor-beta1 activation prevents hepatic fibrosis in vivo. J Hepatol 2003 Nov 2
13 14625694 Suppression of TGF-beta signaling by conophylline via upregulation of c-Jun expression. Cell Mol Life Sci 2003 Nov 3
14 15126250 AT1A-mediated activation of kidney JNK1 and SMAD2 in obstructive uropathy: preservation of kidney tissue mass using candesartan. Am J Physiol Renal Physiol 2004 Sep 2
15 15200418 Curcumin blocks multiple sites of the TGF-beta signaling cascade in renal cells. Kidney Int 2004 Jul 1
16 15569303 AGEs activate mesangial TGF-beta-Smad signaling via an angiotensin II type I receptor interaction. Kidney Int 2004 Dec 1
17 15579626 In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling. Am J Physiol Lung Cell Mol Physiol 2005 Mar 1
18 15613482 Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad. J Biol Chem 2005 Mar 11 1
19 15705182 Transforming growth factor-beta and Smad signalling in kidney diseases. Nephrology (Carlton) 2005 Feb 1
20 15734860 Pioglitazone induces vascular smooth muscle cell apoptosis through a peroxisome proliferator-activated receptor-gamma, transforming growth factor-beta1, and a Smad2-dependent mechanism. Diabetes 2005 Mar 4
21 15769863 Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J Pharmacol Exp Ther 2005 Jun 1
22 15842805 [Changes of fibronectin and type IV collagen expression in cultured rat mesangial cells transfected with Smad 2 vector]. Zhonghua Bing Li Xue Za Zhi 2005 Feb 1
23 15883213 Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism. Circulation 2005 May 17 1
24 15901772 Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models. J Neurosci 2005 May 18 2
25 16644034 Corticosteroids induce the differential expression of TGFbeta isoforms, receptors and signaling in the gastric mucosa of suckling rats. Regul Pept 2006 Jul 15 1
26 16681946 [Effects of peroxisome proliferators-activated receptor gamma agonists on transforming growth factor-beta1 and Smads signal pathway: experiment with rat renal fibroblasts]. Zhonghua Yi Xue Za Zhi 2006 Mar 21 2
27 16790507 Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury. J Am Soc Nephrol 2006 Aug 1
28 16980029 The effects of different immunosuppressants on chronic allograft nephropathy by affecting the transforming growth factor-beta and Smads signal pathways. Transplant Proc 2006 Sep 4
29 17038494 ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells. J Appl Physiol (1985) 2007 Jan 1
30 17074304 Rosiglitazone inhibits angiotensin II-induced CTGF expression in vascular smooth muscle cells - role of PPAR-gamma in vascular fibrosis. Biochem Pharmacol 2007 Jan 15 1
31 17405825 The regulation of FSHbeta transcription by gonadal steroids: testosterone and estradiol modulation of the activin intracellular signaling pathway. Am J Physiol Endocrinol Metab 2007 Jul 2
32 17960594 Atrial natriuretic peptide attenuates high glucose-activated transforming growth factor-beta, Smad and collagen synthesis in renal proximal tubular cells. J Cell Biochem 2008 Apr 15 2
33 18245268 TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury. Am J Physiol Lung Cell Mol Physiol 2008 Apr 1
34 18278065 Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts. Br J Pharmacol 2008 Apr 4
35 18486259 Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. J Hepatol 2008 Nov 4
36 18492773 Aldosterone, but not angiotensin II, increases profibrotic factors in kidney of adrenalectomized stroke-prone spontaneously hypertensive rats. Am J Physiol Endocrinol Metab 2008 Aug 1
37 18583311 Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms. Am J Pathol 2008 Aug 1
38 18679024 Pentoxifylline inhibits transforming growth factor-beta signaling and renal fibrosis in experimental crescentic glomerulonephritis in rats. Am J Nephrol 2009 1
39 18684975 Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506. J Immunol 2008 Aug 15 1
40 18815221 High glucose activates PKC-zeta and NADPH oxidase through autocrine TGF-beta1 signaling in mesangial cells. Am J Physiol Renal Physiol 2008 Dec 1
41 18971187 [Changes in TGF-beta1/Smads signaling pathway in rats with chemical hepatocarcinogenesis]. Nan Fang Yi Ke Da Xue Xue Bao 2008 Oct 1
42 18976289 Nox-2 is a modulator of fibrogenesis in kidney allografts. Am J Transplant 2009 Jan 2
43 18988308 Influence of ginsenoside Rg1, a panaxatriol saponin from Panax notoginseng, on renal fibrosis in rats with unilateral ureteral obstruction. J Zhejiang Univ Sci B 2008 Nov 1
44 19007081 [Preparing of semiconductor quantum dots-Smad2 monoclonal antibody fluorescent probes and testing of its related properties]. Hua Xi Kou Qiang Yi Xue Za Zhi 2008 Oct 2
45 19319146 Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain. J Cereb Blood Flow Metab 2009 Jun 1
46 19374881 Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts. Eur J Pharmacol 2009 Mar 15 1
47 19375729 Losartan preserves erectile function after bilateral cavernous nerve injury via antifibrotic mechanisms in male rats. J Urol 2009 Jun 1
48 19416208 Effects of relaxin on development of mesangial proliferative nephritis. Ann N Y Acad Sci 2009 Apr 1
49 19416222 Relaxin signaling in uterine fibroids. Ann N Y Acad Sci 2009 Apr 1
50 19641115 Ethanol affects transforming growth factor beta1-initiated signals: cross-talking pathways in the developing rat cerebral wall. J Neurosci 2009 Jul 29 6