UPF1 RNA helicase and ATPase ; Homo sapiens






80 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 10376871 mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization? RNA 1999 Jun 1
2 10999600 Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay. RNA 2000 Sep 3
3 11214180 Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway. RNA 2001 Jan 4
4 11544179 Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay. Genes Dev 2001 Sep 1 1
5 12485924 Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease. Ann N Y Acad Sci 2002 Nov 2
6 15175154 The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol Cell 2004 Jun 4 5
7 16452507 Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev 2006 Feb 1 2
8 16732619 Characterization of the antioxidative activity of novel nontoxic neuropeptides by using capillary electrophoresis. Electrophoresis 2006 Jul 2
9 16931876 Crystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1. RNA 2006 Oct 2
10 16934750 A chemiluminescence-based reporter system to monitor nonsense-mediated mRNA decay. Biochem Biophys Res Commun 2006 Oct 13 1
11 17086209 Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells. Oncogene 2007 May 3 1
12 17131291 Comparison of the stability of glutathione and related synthetic tetrapeptides by HPLC and capillary electrophoresis. J Pept Sci 2006 Dec 3
13 17159905 Structural and functional insights into the human Upf1 helicase core. EMBO J 2007 Jan 10 5
14 17576861 Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome. Circulation 2007 Jul 3 1
15 17709397 Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways. Mol Cell Biol 2007 Oct 1
16 17893241 Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies. J Cell Biol 2007 Sep 24 2
17 18256688 Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. EMBO J 2008 Mar 5 2
18 19359157 Execution of nonsense-mediated mRNA decay: what defines a substrate? Curr Opin Cell Biol 2009 Jun 2
19 19417104 SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. Genes Dev 2009 May 1 1
20 19478851 The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay. PLoS Biol 2009 May 26 1
21 20691628 UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps. Mol Cell 2010 Aug 13 3
22 20863723 Nonsense-mediated mRNA decay (NMD) blockage promotes nonsense mRNA stabilization in protein 4.1R deficient cells carrying the 4.1R Coimbra variant of hereditary elliptocytosis. Blood Cells Mol Dis 2010 Dec 15 1
23 20946641 Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay. BMC Genomics 2010 Oct 14 1
24 21145460 Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense- mediated mRNA decay. Cell 2010 Dec 10 1
25 21419344 Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2. Mol Cell 2011 Mar 18 1
26 21596314 Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell 2011 May 20 1
27 21701263 The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA. Cell Cycle 2011 Aug 1 2
28 21965535 N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD. Nucleic Acids Res 2012 Feb 1
29 22611414 Diverse Effects of Glutathione and UPF Peptides on Antioxidant Defense System in Human Erythroleukemia Cells K562. Int J Pept 2012 2
30 22974464 The late steps of plant nonsense-mediated mRNA decay. Plant J 2013 Jan 3
31 23062287 Cigarette smoke-induced differential regulation of glutathione metabolism in bronchial epithelial cells is balanced by an antioxidant tetrapeptide UPF1. Exp Toxicol Pathol 2013 Sep 10
32 23263869 Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity. Proc Natl Acad Sci U S A 2013 Jan 8 5
33 23524536 Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Nat Struct Mol Biol 2013 Apr 1
34 23642263 Mass spectrometry-based proteomics identifies UPF1 as a critical gene expression regulator in MonoMac 6 cells. J Proteome Res 2013 Jun 7 1
35 23681777 Staufen-mediated mRNA decay. Wiley Interdiscip Rev RNA 2013 Jul-Aug 1
36 23704698 Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4. Drug Metab Dispos 2013 Aug 3
37 23826386 MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1. PLoS One 2013 3
38 24056942 mRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decay. Nat Struct Mol Biol 2013 Oct 1
39 24185201 SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay. Biochim Biophys Acta 2013 Dec 1
40 24762188 Characterization of phosphorylation- and RNA-dependent UPF1 interactors by quantitative proteomics. J Proteome Res 2014 Jun 6 2
41 24810251 Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine. Am J Respir Cell Mol Biol 2014 Oct 6
42 24947499 Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiency. RNA 2014 Aug 1
43 25013172 Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6. Nucleic Acids Res 2014 Aug 3
44 25220460 The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex. Cell Rep 2014 Sep 25 1
45 25648792 Two nonsense mutations cause protein C deficiency by nonsense-mediated mRNA decay. Thromb Res 2015 Apr 1
46 25808464 Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics. Nat Commun 2015 Mar 26 1
47 25934542 Increase of a group of PTC(+) transcripts by curcumin through inhibition of the NMD pathway. Biochim Biophys Acta 2015 Aug 4
48 26536230 E-Cigarette Affects the Metabolome of Primary Normal Human Bronchial Epithelial Cells. PLoS One 2015 1
49 26759305 The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma. J Exp Clin Cancer Res 2016 Jan 13 1
50 26863136 In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis. PLoS One 2016 1