Title : Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine.

Pub. Date : 2014 Oct

PMID : 24810251






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Principal component analysis, based on untargeted mass spectra, indicated that treatment of CSC-exposed HBECs with O-methyl-L-tyrosinyl-gamma-L-glutamyl-L-cysteinylglycine (UPF1) acted faster than did N-acetylcysteine to revert the effect of CSC. o-methyl-l-tyrosinyl-gamma-l-glutamyl-l-cysteinylglycine UPF1 RNA helicase and ATPase Homo sapiens
2 Principal component analysis, based on untargeted mass spectra, indicated that treatment of CSC-exposed HBECs with O-methyl-L-tyrosinyl-gamma-L-glutamyl-L-cysteinylglycine (UPF1) acted faster than did N-acetylcysteine to revert the effect of CSC. Acetylcysteine UPF1 RNA helicase and ATPase Homo sapiens
3 Furthermore, UPF1 up-regulated the contents of phospholipid species identified as phosphatidylcholines and phosphatidylethanolamines in the CSC-exposed HBECs, indicating possible suppression of inflammatory processes along with an increase in spermidine as an endogenous cytoprotector. Phospholipids UPF1 RNA helicase and ATPase Homo sapiens
4 Furthermore, UPF1 up-regulated the contents of phospholipid species identified as phosphatidylcholines and phosphatidylethanolamines in the CSC-exposed HBECs, indicating possible suppression of inflammatory processes along with an increase in spermidine as an endogenous cytoprotector. Phosphatidylcholines UPF1 RNA helicase and ATPase Homo sapiens
5 Furthermore, UPF1 up-regulated the contents of phospholipid species identified as phosphatidylcholines and phosphatidylethanolamines in the CSC-exposed HBECs, indicating possible suppression of inflammatory processes along with an increase in spermidine as an endogenous cytoprotector. Phosphatidylethanolamines UPF1 RNA helicase and ATPase Homo sapiens
6 Furthermore, UPF1 up-regulated the contents of phospholipid species identified as phosphatidylcholines and phosphatidylethanolamines in the CSC-exposed HBECs, indicating possible suppression of inflammatory processes along with an increase in spermidine as an endogenous cytoprotector. Spermidine UPF1 RNA helicase and ATPase Homo sapiens