DNA polymerase kappa ; Homo sapiens






41 Article(s)
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1 6669376 Complexes of polyadenylic acid and the methyl esters of amino acids. Orig Life 1983 Dec 1
2 11733032 Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription. Genes Cells 2001 Nov 1
3 11735400 Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV. Biochemistry 2001 Dec 18 1
4 11919199 Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. J Biol Chem 2002 May 31 1
5 11994005 Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Biochemistry 2002 May 14 2
6 12145297 Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. J Biol Chem 2002 Oct 4 1
7 12432099 Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene. Proc Natl Acad Sci U S A 2002 Nov 26 3
8 12509229 Activities of human DNA polymerase kappa in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion. DNA Repair (Amst) 2002 Jul 17 1
9 15817457 DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint. J Biol Chem 2005 Jun 10 3
10 16055723 Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Mol Cell Biol 2005 Aug 1
11 16751196 Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa. J Biol Chem 2006 Jul 28 1
12 18079151 DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. Nucleic Acids Res 2008 Feb 4
13 18434313 Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links. J Biol Chem 2008 Jun 20 1
14 18788085 Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE). J Pathol 2008 Nov 1
15 18931375 The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Nucleic Acids Res 2008 Nov 4
16 19341290 The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa. Biochemistry 2009 May 26 1
17 19492058 Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. PLoS One 2009 Jun 2 1
18 19542228 Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct. J Biol Chem 2009 Aug 14 1
19 19674572 A novel method for assessing elbow pain resulting from epicondylitis. J Chiropr Med 2002 Summer 1
20 20952260 Bypass of N²-ethylguanine by human DNA polymerase κ. DNA Repair (Amst) 2011 Jan 2 1
21 21078407 Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa. Mutat Res 2011 Jan 10 3
22 21454642 The roles of DNA polymerases κ and ι in the error-free bypass of N2-carboxyalkyl-2'-deoxyguanosine lesions in mammalian cells. J Biol Chem 2011 May 20 2
23 22227292 Characterization of human DNA polymerase κ promoter in response to benzo[a]pyrene diol epoxide. Environ Toxicol Pharmacol 2012 Mar 10
24 22804710 Mutagenic bypass of 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) by DNA polymerase κ in human cells. Chem Res Toxicol 2012 Aug 20 2
25 23056190 A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ. PLoS One 2012 4
26 24461735 In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ. DNA Repair (Amst) 2014 Mar 7
27 24948471 Association of POLK polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients. Cell Biochem Biophys 2014 Nov 1
28 25065501 Elucidation of kinetic mechanisms of human translesion DNA polymerase κ using tryptophan mutants. FEBS J 2014 Oct 1
29 25294835 The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa. Nucleic Acids Res 2014 Oct 29 2
30 25899385 Noncognate DNA damage prevents the formation of the active conformation of the Y-family DNA polymerases DinB and DNA polymerase κ. FEBS J 2015 Jul 2
31 26651356 Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells. Chem Res Toxicol 2016 Jan 19 1
32 26960975 The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling. Cancer Res 2016 Apr 15 1
33 27034468 Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ. Nucleic Acids Res 2016 Jun 2 3
34 27490094 Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1. Chem Res Toxicol 2016 Sep 19 1
35 28140505 N<sup>2</sup> -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ. Angew Chem Int Ed Engl 2017 Mar 1 3
36 28391554 Translesion Synthesis DNA Polymerase Kappa Is Indispensable for DNA Repair Synthesis in Cisplatin Exposed Dorsal Root Ganglion Neurons. Mol Neurobiol 2018 Mar 1
37 29715472 Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. J Mol Biol 2018 May 25 1
38 30862140 [Genetic variation in DNA polymerase kappa gene is associated with the prognosis after platinum-based chemotherapy in small cell lung cancer patients]. Zhonghua Zhong Liu Za Zhi 2019 Feb 23 3
39 31082191 Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms. ACS Chem Biol 2019 Jun 21 2
40 31108449 Building surface materials as sources of micropollutants in building runoff: A pilot study. Sci Total Environ 2019 Aug 25 1
41 31286773 Kinetic Investigation of Translesion Synthesis across a 3-Nitrobenzanthrone-Derived DNA Lesion Catalyzed by Human DNA Polymerase Kappa. Chem Res Toxicol 2019 Aug 19 1