SQ 29548






49 Article(s)
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1 1320340 Role of superoxide anion and endothelium in vasoconstrictor action of prostaglandin endoperoxide. Am J Physiol 1992 Jun 1
2 1387436 Reduced glomerular thromboxane receptor sites and vasoconstrictor responses in diabetic rats. Kidney Int 1992 Apr 1
3 1833525 Mechanism for homologous downregulation of thromboxane A2 receptors in cultured human chronic myelogenous leukemia (K562) cells. J Pharmacol Exp Ther 1991 Oct 1
4 2013478 Role of prostanoids in renin-dependent and renin-independent hypertension. Hypertension 1991 Apr 1
5 2139470 Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats. J Pharmacol Exp Ther 1990 Apr 1
6 2141663 Characterization of thromboxane A2/prostaglandin H2 receptors in human vascular smooth muscle cells. Life Sci 1990 1
7 3377072 Bradykinin-induced vasoconstriction and thromboxane release in perfused human placenta. Am J Physiol 1988 Jun 1
8 7582454 Activation of rabbit platelets by Ca2+ influx and thromboxane A2 release in an external Ca(2+)-dependent manner by zooxanthellatoxin-A, a novel polyol. Br J Pharmacol 1995 Jun 1
9 8071836 Characterization of human peripheral blood monocyte thromboxane A2 receptors. J Pharmacol Exp Ther 1994 Aug 1
10 8481403 Glomerular thromboxane A2/prostaglandin H2 receptors: characterization and effect of adriamycin-induced nephrotic syndrome. Biochim Biophys Acta 1993 Apr 30 1
11 8528563 Characterization of the thromboxane (TP-) receptor subtype involved in proliferation in cultured vascular smooth muscle cells of rat. Br J Pharmacol 1995 Sep 1
12 8769820 Stimulation of rat mesangial cell thromboxane A2 receptors inhibits particulate but not soluble guanylyl cyclase. Am J Physiol 1996 Jan 1
13 8806891 Effects of tumor necrosis factor and interleukin-1 on the constriction induced by angiotensin II in rat aorta. J Appl Physiol (1985) 1996 Jun 1
14 8847278 Short exposure to endotoxin increases the constriction induced by angiotensin II in rat aorta. J Appl Physiol (1985) 1995 Dec 2
15 8853359 Differences between cytokine effects in the microcirculation of the rat. Am J Physiol 1996 Sep 1
16 9038917 Contractile actions of C5a on isolated porcine coronary resistance and conductance arteries. Am J Physiol 1997 Jan 1
17 9054746 Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and then reoxygenated. Circulation 1997 Feb 18 1
18 9099206 Isoprostanes: free radical-generated prostaglandins with constrictor effects on cerebral arterioles. Stroke 1997 Apr 1
19 9416330 Dependence of basal cerebral blood flow and cerebral vascular resistance in spontaneously hypertensive rats upon vasoconstrictor prostanoids. Acta Neurochir Suppl 1997 1
20 10205005 The vasoconstrictor effect of 8-epi prostaglandin F2alpha in the hypoxic rat heart. Br J Pharmacol 1999 Mar 1
21 10846009 PGH(2)-TxA(2)-receptor blockade restores vasoreactivity in a new rodent model of genetic hypertension. J Appl Physiol (1985) 2000 Jun 2
22 11043604 Phorbol ester-induced phosphoinositide hydrolysis in rat aorta: role of cyclooxygenase products. Life Sci 2000 Sep 1 1
23 11483590 Up-regulation of endothelial cyclooxygenase-2 and prostanoid synthesis by platelets. Role of thromboxane A2. J Biol Chem 2001 Oct 12 1
24 11588527 Vascular responses to endothelin-1, angiotensin-II, and U46619 in glycerol-induced acute renal failure. J Cardiovasc Pharmacol 2001 Oct 1
25 11740157 Influence of type II diabetes on arterial tone and endothelial function in murine mesenteric resistance arteries. J Vasc Res 2001 Nov-Dec 1
26 11756341 High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes 2002 Jan 1
27 12231564 Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats. Arterioscler Thromb Vasc Biol 2002 Sep 1 2
28 12749591 Chronic exposure to TXA2 increases expression of ROCKI in human myometrial cells. Prostaglandins Other Lipid Mediat 2003 Apr 1
29 12911598 TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets. J Thromb Haemost 2003 Aug 1
30 14504133 Effects of TRA-418, a novel TP-receptor antagonist, and IP-receptor agonist, on human platelet activation and aggregation. Br J Pharmacol 2003 Nov 2
31 14517679 Rhythmical contractions in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats. Pflugers Arch 2003 Nov 1
32 16079262 IGF-I-induced enhancement of contractile response in organ-cultured aortae from diabetic rats is mediated by sustained thromboxane A2 release from endothelial cells. J Endocrinol 2005 Aug 1
33 16186418 CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo. Circulation 2005 Oct 4 3
34 16905600 Chronic hyperglycemia impairs functional vasodilation via increasing thromboxane-receptor-mediated vasoconstriction. Am J Physiol Heart Circ Physiol 2007 Jan 1
35 17766473 Roles of vasoconstrictor prostaglandins, COX-1 and -2, and AT1, AT2, and TP receptors in a rat model of early 2K,1C hypertension. Am J Physiol Heart Circ Physiol 2007 Nov 1
36 18032781 Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling. Arterioscler Thromb Vasc Biol 2008 Jan 6
37 19696359 Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats. J Appl Physiol (1985) 2009 Oct 2
38 21839852 17-Octadecynoic acid improves contractile response to angiotensin II by releasing vasocontrictor prostaglandins. Prostaglandins Other Lipid Mediat 2012 Jan 1
39 22565502 Isoprostanes as physiological mediators of transition to newborn life: novel mechanisms regulating patency of the term and preterm ductus arteriosus. Pediatr Res 2012 Aug 1
40 23475395 Histamine, carbachol, and serotonin induce hyperresponsiveness to ATP in guinea pig tracheas: involvement of COX-2 pathway. Pflugers Arch 2013 Aug 1
41 23741477 Acyl chain-dependent effect of lysophosphatidylcholine on endothelium-dependent vasorelaxation. PLoS One 2013 1
42 23995773 Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. Pflugers Arch 2014 Mar 1
43 25921923 Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors. Vascul Pharmacol 2015 Oct 1
44 27775054 Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury. Sci Rep 2016 Oct 24 7
45 28677768 Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS‑induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF‑κB signaling pathways. Mol Med Rep 2017 Sep 8
46 28780751 Role of curcumin in PLD activation by Arf6-cytohesin1 signaling axis in U46619-stimulated pulmonary artery smooth muscle cells. Mol Cell Biochem 2018 Jan 1
47 28822840 Role of ADP ribosylation factor6- Cytohesin1-PhospholipaseD signaling axis in U46619 induced activation of NADPH oxidase in pulmonary artery smooth muscle cell membrane. Arch Biochem Biophys 2017 Nov 1 2
48 29431644 Induction of microRNA-199 by Nitric Oxide in Endothelial Cells Is Required for Nitrovasodilator Resistance via Targeting of Prostaglandin I2 Synthase. Circulation 2018 Jul 24 1
49 29620149 Thromboxane A2 receptor antagonist SQ29548 attenuates SH‑SY5Y neuroblastoma cell impairments induced by oxidative stress. Int J Mol Med 2018 Jul 9