Title : Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling.

Pub. Date : 2008 Jan

PMID : 18032781






6 Functional Relationships(s)
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1 The activation of JNK by U46619 resulted in enhanced phosphorylation and nuclear translocation of c-Jun associated with an enhanced activation of activator protein (AP)-1, which were abolished by SQ29548, a TPr antagonist, or the JNK inhibitor. SQ 29548 mitogen-activated protein kinase 8 Homo sapiens
2 The activation of JNK by U46619 resulted in enhanced phosphorylation and nuclear translocation of c-Jun associated with an enhanced activation of activator protein (AP)-1, which were abolished by SQ29548, a TPr antagonist, or the JNK inhibitor. SQ 29548 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 The activation of JNK by U46619 resulted in enhanced phosphorylation and nuclear translocation of c-Jun associated with an enhanced activation of activator protein (AP)-1, which were abolished by SQ29548, a TPr antagonist, or the JNK inhibitor. SQ 29548 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens
4 The activation of JNK by U46619 resulted in enhanced phosphorylation and nuclear translocation of c-Jun associated with an enhanced activation of activator protein (AP)-1, which were abolished by SQ29548, a TPr antagonist, or the JNK inhibitor. SQ 29548 mitogen-activated protein kinase 8 Homo sapiens
5 Furthermore, U46619 enhanced IL-1beta-induced THP-1 monocyte binding to VSMCs, which was inhibited by SQ29548 or SP600125. SQ 29548 interleukin 1 beta Homo sapiens
6 Furthermore, U46619 enhanced IL-1beta-induced THP-1 monocyte binding to VSMCs, which was inhibited by SQ29548 or SP600125. SQ 29548 GLI family zinc finger 2 Homo sapiens