| 1 | 15833884 | Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. | Cancer Res | 2005 Apr 15 |
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| 2 | 19138991 | Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53. | Cancer Prev Res (Phila) | 2008 Nov |
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| 3 | 23727179 | Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages. | Food Chem Toxicol | 2013 Aug |
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| 4 | 24121102 | Kava chalcone, flavokawain A, inhibits urothelial tumorigenesis in the UPII-SV40T transgenic mouse model. | Cancer Prev Res (Phila) | 2013 Dec |
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| 5 | 25379458 | Dietary feeding of Flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice. | Toxicol Rep | 2014 |
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| 6 | 26179368 | In Vivo Anti-Tumor Effects of Flavokawain A in 4T1 Breast Cancer Cell-Challenged Mice. | Anticancer Agents Med Chem | 2015 |
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| 7 | 26497688 | Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model. | Oncotarget | 2015 Dec 8 |
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| 8 | 27318274 | Flavokawain A inhibits Cytochrome P450 in in vitro metabolic and inhibitory investigations. | J Ethnopharmacol | 2016 Sep 15 |
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| 9 | 28335434 | Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin. | Molecules | 2017 Mar 14 |
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| 10 | 30250282 | Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma. | Sci Rep | 2018 Sep 24 |
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| 11 | 30549180 | Chalcone flavokawain A attenuates TGF-β1-induced fibrotic pathology via inhibition of ROS/Smad3 signaling pathways and induction of Nrf2/ARE-mediated antioxidant genes in vascular smooth muscle cells. | J Cell Mol Med | 2019 Feb |
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| 12 | 32617135 | Suppression of LPS-Induced Inflammation by Chalcone Flavokawain A through Activation of Nrf2/ARE-Mediated Antioxidant Genes and Inhibition of ROS/NF<i>κ</i>B Signaling Pathways in Primary Splenocytes. | Oxid Med Cell Longev | 2020 |
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| 13 | 32623326 | Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma. | Transl Oncol | 2020 Oct |
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| 14 | 32848393 | Synergistic Combination of Sodium Aescinate-Stabilized, Polymer-Free, Twin-Like Nanoparticles to Reverse Paclitaxel Resistance. | Int J Nanomedicine | 2020 |
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| 15 | 34822529 | Anti-Apoptotic Effect of Flavokawain A on Ochratoxin-A-Induced Endothelial Cell Injury by Attenuation of Oxidative Stress via PI3K/AKT-Mediated Nrf2 Signaling Cascade. | Toxins (Basel) | 2021 Oct 21 |
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| 16 | 35335874 | Chemoprevention of Urothelial Cell Carcinoma Tumorigenesis by Dietary Flavokawain A in UPII-Mutant Ha-ras Transgenic Mice. | Pharmaceutics | 2022 Feb 24 |
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