EHT 1864






25 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 22440899 Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation. J Am Soc Nephrol 2012 Jun 1
2 22613348 Hyperstimulation of macropinocytosis leads to lysosomal dysfunction during exposure to methamphetamine in SH-SY5Y cells. Brain Res 2012 Jul 23 1
3 23999236 DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac. Biochim Biophys Acta 2013 Dec 4
4 24240542 Identification of key signaling molecules involved in the activation of the swelling-activated chloride current in human glioblastoma cells. J Membr Biol 2014 Jan 1
5 24283667 Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies. J Thromb Haemost 2014 Feb 1
6 24297853 The small GTPase Rac1 is required for smooth muscle contraction. J Physiol 2014 Mar 1 1
7 24603367 Local mineralocorticoid receptor activation and the role of Rac1 in obesity-related diabetic kidney disease. Nephron Exp Nephrol 2014 5
8 25628054 Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets. J Thromb Haemost 2015 May 4
9 25631101 Inhibition of prostate smooth muscle contraction and prostate stromal cell growth by the inhibitors of Rac, NSC23766 and EHT1864. Br J Pharmacol 2015 Jun 1
10 25816094 Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells. PLoS One 2015 3
11 26645485 Transmigration characteristics of breast cancer and melanoma cells through the brain endothelium: Role of Rac and PI3K. Cell Adh Migr 2016 May 3 1
12 26939003 Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice. PLoS One 2016 1
13 28220272 Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells. Apoptosis 2017 May 4
14 28423521 Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer. Oncotarget 2017 Mar 28 12
15 28796249 Rho inhibition by lovastatin affects apoptosis and DSB repair of primary human lung cells in vitro and lung tissue in vivo following fractionated irradiation. Cell Death Dis 2017 Aug 10 1
16 29055784 Rac1 modulates G-protein-coupled receptor-induced bronchial smooth muscle contraction. Eur J Pharmacol 2018 Jan 5 4
17 29223502 Hydroxyl radical production via NADPH oxidase in rat striatum due to carbon monoxide poisoning. Toxicology 2018 Feb 1 6
18 30697954 Up-regulation of Rac1 in the bronchial smooth muscle of murine experimental asthma. Basic Clin Pharmacol Toxicol 2019 Jul 2
19 30811062 New strategies for inhibition of non-adrenergic prostate smooth muscle contraction by pharmacologic intervention. Prostate 2019 May 4
20 31217360 Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production. JCI Insight 2019 Jun 20 1
21 31243195 Increased Rac1 Activation in the Enhanced Carbachol-Induced Bronchial Smooth Muscle Contraction of Repeatedly Antigen-Challenged Mice. Biol Pharm Bull 2019 Sep 1 1
22 32317972 Inhibition of Female and Male Human Detrusor Smooth Muscle Contraction by the Rac Inhibitors EHT1864 and NSC23766. Front Pharmacol 2020 1
23 33542087 Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling. Thorax 2021 Apr 4
24 34172833 Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia. Commun Biol 2021 Jun 25 2
25 35409124 Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphorylation. Int J Mol Sci 2022 Mar 29 6