Ethionamide






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1 2529663 The effect of various anticoagulant/antiplatelet mixtures on determination of plasminogen activator inhibitor, platelet proteins and hemostasis parameters. Thromb Haemost 1989 Jun 30 1
2 4387664 [Studies on the endogenous metabolism of mycobacteria. 4. On the influence of ethionamide on the endogenous metabolism of Myc. smegm]. Z Naturforsch B 1968 Jul 1
3 4963957 [On the inhibition of catalase activity by 2-ethyl-isonicotinic acid thioamide]. Naturwissenschaften 1966 Feb 1
4 6418158 Haemoglobin potentiates the respiration-inhibitory action of lipoxygenases via its pseudolipohydroperoxidase activity. Biomed Biochim Acta 1983 1
5 10625209 Detection of decreased response to activated protein C during pregnancy by an endogenous thrombin potential-based assay. Semin Thromb Hemost 1999 1
6 12557715 [A case of advanced gastric adenocarcinoma with mild elevation of serum SCC that responded remarkably to adjuvant chemotherapy of ADM, CDDP, ETP and 5-FU (ACVF)]. Gan To Kagaku Ryoho 2003 Jan 1
7 12869355 Differential effects of oral and transdermal estrogen/progesterone regimens on sensitivity to activated protein C among postmenopausal women: a randomized trial. Arterioscler Thromb Vasc Biol 2003 Sep 1 1
8 15236969 Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance. J Mol Biol 2004 Jul 23 2
9 15528841 Inhibitory effect of antituberculosis drugs on human cytochrome P450-mediated activities. J Pharmacol Sci 2004 Nov 1
10 16895935 Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria. J Antimicrob Chemother 2006 Oct 4
11 18930751 Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes. Toxicol Appl Pharmacol 2008 Dec 15 3
12 19589782 Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism. J Biol Chem 2009 Sep 25 1
13 19859963 Axon responses of embryonic stem cell-derived dopaminergic neurons to semaphorins 3A and 3C. J Neurosci Res 2010 Apr 1
14 19861006 Ethionamide cross- and co-resistance in children with isoniazid-resistant tuberculosis. Int J Tuberc Lung Dis 2009 Nov 1
15 20863819 Bioactivation of antituberculosis thioamide and thiourea prodrugs by bacterial and mammalian flavin monooxygenases. Chem Biol Interact 2011 Jun 30 1
16 22026918 Comparative analysis of mycobacterial NADH pyrophosphatase isoforms reveals a novel mechanism for isoniazid and ethionamide inactivation. Mol Microbiol 2011 Dec 6
17 22035573 Trunk weighted obesity, cholesterol levels and low grade inflammation are main determinants for enhanced thrombin generation. Atherosclerosis 2012 Jan 1
18 22098589 Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors. J Med Chem 2012 Jan 12 1
19 22389470 HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer. Mol Cancer Ther 2012 Apr 2
20 22520259 Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor. Bioorg Med Chem Lett 2012 May 15 1
21 23146620 Can inhA mutation predict ethionamide resistance? Int J Tuberc Lung Dis 2013 Jan 4
22 23352980 PIM1 kinase inhibitors induce radiosensitization in non-small cell lung cancer cells. Pharmacol Res 2013 Apr 2
23 23476046 Blood hypomethylation of inflammatory genes mediates the effects of metal-rich airborne pollutants on blood coagulation. Occup Environ Med 2013 Jun 3
24 23826181 Thrombin generation in the Glasgow Myocardial Infarction Study. PLoS One 2013 2
25 23926305 Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL. Blood 2013 Sep 19 2
26 24192167 Structural and docking studies of potent ethionamide boosters. Acta Crystallogr C 2013 Nov 1
27 24247125 Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis. Antimicrob Agents Chemother 2014 1
28 24329989 Immunophenotypic analysis of T-acute lymphoblastic leukemia. A CD5-based ETP-ALL perspective of non-ETP T-ALL. Eur J Haematol 2014 Mar 2
29 24566628 An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition. Infect Immun 2014 May 1
30 24687960 Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential. J Exp Med 2014 Apr 7 4
31 24708207 Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003. Br J Haematol 2014 Aug 1
32 25048293 Hydrogenation of imines catalyzed by trisphosphine-substituted molybdenum and tungsten nitrosyl hydrides and co-catalytic acid. Chem Asian J 2014 Oct 3
33 25199009 Isoniazid and rifampicin resistance mutations and their effect on second-line anti-tuberculosis treatment. Int J Tuberc Lung Dis 2014 Aug 1
34 25269127 The development and implementation of, and first years' experience with, a massive/emergency transfusion protocol (damage control hematology protocol) in a Veterans Affairs hospital. Mil Med 2014 Oct 1
35 25767050 Novel pseudo[2]rotaxanes constructed by the self-assembly of dibenzyl tetramethylene bis-carbamate derivatives and per-ethylated pillar[5]arene. Chem Commun (Camb) 2015 Apr 18 2
36 26094899 Inhibitory Potential of Twenty Five Anti-tuberculosis Drugs on CYP Activities in Human Liver Microsomes. Biol Pharm Bull 2015 1
37 26332235 High Prevalence of inhA Promoter Mutations among Patients with Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa. PLoS One 2015 1
38 26544630 Analogues of ethionamide, a drug used for multidrug-resistant tuberculosis, exhibit potent inhibition of tyrosinase. Eur J Med Chem 2015 Dec 1 4
39 26586461 Thrombin generation and other coagulation parameters in a patient with homozygous congenital protein S deficiency on treatment with rivaroxaban. Int J Hematol 2016 Feb 1
40 26586647 A review of the use of ethionamide and prothionamide in childhood tuberculosis. Tuberculosis (Edinb) 2016 Mar 4
41 26708503 Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells. Toxicol Appl Pharmacol 2016 Feb 1 7
42 27148573 Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case. Cold Spring Harb Mol Case Stud 2015 Oct 5
43 27393546 Detection of katG and inhA mutations to guide isoniazid and ethionamide use for drug-resistant tuberculosis. Int J Tuberc Lung Dis 2016 Aug 2
44 28043598 Investigation of isoniazid and ethionamide cross-resistance by whole genome sequencing and association with poor treatment outcomes of multidrug-resistant tuberculosis patients in South Africa. Int J Mycobacteriol 2016 Dec 3
45 28819071 Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. J Pharmacol Exp Ther 2017 Nov 2
46 28957755 Multiple receptor conformers based molecular docking study of fluorine enhanced ethionamide with mycobacterium enoyl ACP reductase (InhA). J Mol Graph Model 2017 Oct 1
47 29067094 Dasatinib and chemotherapy in a patient with early T-cell precursor acute lymphoblastic leukemia and <i>NUP214-ABL1</i> fusion: A case report. Exp Ther Med 2017 Nov 2
48 29878384 Development of a Physiologically Based Pharmacokinetic Model of Ethionamide in the Pediatric Population by Integrating Flavin-Containing Monooxygenase 3 Maturational Changes Over Time. J Clin Pharmacol 2018 Oct 3
49 30684598 In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus. Int J Pharm 2019 Mar 25 4
50 30690726 Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug-Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3. J Clin Pharmacol 2019 Jun 11