Title : Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria.

Pub. Date : 2006 Oct

PMID : 16895935






4 Functional Relationships(s)
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1 RESULTS: Data indicated that the intracellular metabolization of ethionamide strictly depends on the presence of the monooxygenase EthA and that EthA-dependent activation of ethionamide is coupled to a precise molecular sorting mechanism of the ethionamide metabolites. Ethionamide sodium voltage-gated channel alpha subunit 9 Homo sapiens
2 RESULTS: Data indicated that the intracellular metabolization of ethionamide strictly depends on the presence of the monooxygenase EthA and that EthA-dependent activation of ethionamide is coupled to a precise molecular sorting mechanism of the ethionamide metabolites. Ethionamide sodium voltage-gated channel alpha subunit 9 Homo sapiens
3 RESULTS: Data indicated that the intracellular metabolization of ethionamide strictly depends on the presence of the monooxygenase EthA and that EthA-dependent activation of ethionamide is coupled to a precise molecular sorting mechanism of the ethionamide metabolites. Ethionamide sodium voltage-gated channel alpha subunit 9 Homo sapiens
4 RESULTS: Data indicated that the intracellular metabolization of ethionamide strictly depends on the presence of the monooxygenase EthA and that EthA-dependent activation of ethionamide is coupled to a precise molecular sorting mechanism of the ethionamide metabolites. Ethionamide sodium voltage-gated channel alpha subunit 9 Homo sapiens