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5 | 11090117 | Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism. | Br J Pharmacol | 2000 Dec |
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8 | 11387395 | Group I mGluRs coupled to G proteins are regulated by tyrosine kinase in dopamine neurons of the rat midbrain. | J Neurophysiol | 2001 Jun |
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10 | 11543761 | Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats. | Neuropharmacology | 2001 Sep |
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11 | 11591458 | Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons. | Neuroscience | 2001 |
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12 | 11743947 | Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia. | Brain Res | 2001 Dec 20 |
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14 | 11897107 | Group I metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons. | Neuropharmacology | 2002 Mar |
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15 | 11923431 | Metabotropic glutamate receptor 5 upregulation in A-fibers after spinal nerve injury: 2-methyl-6-(phenylethynyl)-pyridine (MPEP) reverses the induced thermal hyperalgesia. | J Neurosci | 2002 Apr 1 |
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18 | 12077217 | The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala. | J Neurosci | 2002 Jun 15 |
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21 | 12097518 | Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism. | J Neurosci | 2002 Jul 1 |
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22 | 12117582 | Neuronal and glial mGluR5 modulation prevents stretch-induced enhancement of NMDA receptor current. | Pharmacol Biochem Behav | 2002 Sep |
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24 | 12117592 | Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats. | Pharmacol Biochem Behav | 2002 Sep |
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25 | 12117593 | Differential effects of mGluR1 and mGlur5 antagonism on spatial learning in rats. | Pharmacol Biochem Behav | 2002 Sep |
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26 | 12139116 | Behavioral effects of the selective blockade of metabotropic glutamate receptor subtype 5 in experimental hypoxia. | Pol J Pharmacol | 2002 Mar-Apr |
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27 | 12231639 | Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei. | J Physiol | 2002 Sep 15 |
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28 | 12354644 | Metabotropic glutamate receptor involvement in phosphoinositide hydrolysis stimulation by an endogenous Na(+), K(+)-ATPase inhibitor and ouabain in neonatal rat brain. | Brain Res Dev Brain Res | 2002 Oct 20 |
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29 | 12364493 | Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices. | J Neurophysiol | 2002 Oct |
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30 | 12373538 | The role of striatal metabotropic glutamate receptors in degeneration of dopamine neurons: review article. | Amino Acids | 2002 |
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31 | 12473093 | Reduced stress-induced hyperthermia in mGluR5 knockout mice. | Eur J Neurosci | 2002 Dec |
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32 | 12494407 | The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse. | Synapse | 2003 Mar |
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33 | 12505681 | mGlu5 receptor antagonist decreases Fos expression in spinal neurons after noxious visceral stimulation. | Brain Res | 2003 Jan 17 |
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34 | 12527469 | The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity. | Neuropharmacology | 2002 Dec |
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35 | 12527470 | Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist. | Neuropharmacology | 2002 Dec |
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36 | 12559117 | Corticostriatal LTP requires combined mGluR1 and mGluR5 activation. | Neuropharmacology | 2003 Jan |
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37 | 12575822 | Neuroprotective activity of metabotropic glutamate receptor ligands. | Adv Exp Med Biol | 2002 |
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38 | 12660307 | Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents. | J Pharmacol Exp Ther | 2003 Jul |
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39 | 12668042 | Metabotropic glutamate receptor 5 antagonist-induced stimulation of hypothalamic-pituitary-adrenal axis activity: interaction with serotonergic systems. | Neuropharmacology | 2003 Apr |
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40 | 12682710 | The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. | Psychopharmacology (Berl) | 2003 May |
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41 | 12727324 | The mGluR5 selective antagonist 6-methyl-2-(phenylethynyl)-pyridine reduces the spinal neuron pain-related activity in mononeuropathic rats. | Neurosci Lett | 2003 May 15 |
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42 | 12742254 | MPEP, a selective metabotropic glutamate receptor 5 antagonist, attenuates conditioned taste aversion in rats. | Behav Brain Res | 2003 May 15 |
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43 | 12763091 | Role of metabotropic glutamate receptor subtype 5 (mGluR5) in the maintenance of cold hypersensitivity following a peripheral mononeuropathy in the rat. | Neuropharmacology | 2003 Jun |
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44 | 12907309 | Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats. | Neuropharmacology | 2003 Sep |
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45 | 13679408 | Differential roles of mGluR1 and mGluR5 in brief and prolonged nociceptive processing in central amygdala neurons. | J Neurophysiol | 2004 Jan |
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46 | 14500738 | Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine. | Mol Pharmacol | 2003 Oct |
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47 | 14519508 | Long term potentiation varies with layer in rat visual cortex. | Brain Res | 2003 Oct 31 |
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48 | 14552898 | Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents. | Exp Neurol | 2003 Oct |
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49 | 14726993 | Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice. | Psychopharmacology (Berl) | 2004 Jul |
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50 | 14735132 | mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior. | Neuropsychopharmacology | 2004 May |
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