Title : The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice.

Pub. Date : 2003 May

PMID : 12682710






2 Functional Relationships(s)
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1 The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. 6-methyl-2-(phenylethynyl)pyridine glutamate receptor, ionotropic, kainate 1 Mus musculus
2 OBJECTIVES: The present study investigated the effects of the mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) on intravenous nicotine self-administration in Wistar rats and DBA/2J mice. 6-methyl-2-(phenylethynyl)pyridine glutamate receptor, ionotropic, kainate 1 Mus musculus