Anastrozole






245 Article(s)
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1 9152599 Inhibition of human drug metabolizing cytochromes P450 by anastrozole, a potent and selective inhibitor of aromatase. Drug Metab Dispos 1997 May 3
2 9394367 Anastrozole: a new selective nonsteroidal aromatase inhibitor. Oncology (Williston Park) 1997 Nov 3
3 9619713 Clinical efficacy of the aromatase inhibitor anastrozole in relation to prolactin secretion in heavily pretreated metastatic breast cancer. Tumori 1998 Jan-Feb 2
4 10623624 Synthesis and biochemical evaluation of novel inhibitors of aromatase (AR) using an enhanced representation of the active site of AR derived from the consideration of the reaction mechanism. Biochem Biophys Res Commun 2000 Jan 7 1
5 10732791 Use of aromatase inhibitors in breast carcinoma. Endocr Relat Cancer 1999 Mar 1
6 10999781 Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback. J Clin Endocrinol Metab 2000 Sep 1
7 11078488 Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group. J Clin Oncol 2000 Nov 15 2
8 11096352 Gonadotropins stimulate growth of MCF-7 human breast cancer cells by promoting intracellular conversion of adrenal androgens to estrogens. Oncology 2000 1
9 11329794 [Development of a novel aromatase inhibitor, anastrozole (Arimidex)--its basic and clinical studies]. Gan To Kagaku Ryoho 2001 Apr 4
10 11350888 Influence of neoadjuvant anastrozole (Arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer. Clin Cancer Res 2001 May 1
11 11384878 Intracellular aromatase and its relevance to the pharmacological efficacy of aromatase inhibitors. J Steroid Biochem Mol Biol 2001 Jan-Mar 1
12 11550075 Aromatase, aromatase inhibitors, and breast cancer. Am J Ther 2001 Sep-Oct 1
13 11745278 Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma. Cancer 2001 Nov 1 1
14 11821457 Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. J Clin Oncol 2002 Feb 1 3
15 11850213 Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy. J Steroid Biochem Mol Biol 2001 Dec 2
16 11904449 Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis. Proc Natl Acad Sci U S A 2002 Mar 19 5
17 11916226 Are differences in the available aromatase inhibitors and inactivators significant? Clin Cancer Res 2001 Dec 1
18 11916231 Preliminary data from ongoing adjuvant aromatase inhibitor trials. Clin Cancer Res 2001 Dec 1
19 11983488 Short-term effects of anastrozole treatment on insulin-like growth factor system in postmenopausal advanced breast cancer patients. J Steroid Biochem Mol Biol 2002 Apr 2
20 12113240 Aromatase inhibitors in breast cancer therapy. Expert Rev Anticancer Ther 2002 Apr 1
21 12177804 Effect of neoadjuvant treatment with anastrozole on tumour histology in postmenopausal women with large operable breast cancer. Br J Cancer 2002 Jul 29 1
22 12186625 Anastrozole in the management of breast cancer. Expert Opin Pharmacother 2002 Sep 1
23 12364416 The novel use of very high doses of cabergoline and a combination of testosterone and an aromatase inhibitor in the treatment of a giant prolactinoma. J Clin Endocrinol Metab 2002 Oct 1
24 12402060 The evolving role of aromatase inhibitors in breast cancer. Int J Clin Oncol 2002 Oct 5
25 12421108 Anastrozole: in early breast cancer. Drugs 2002 1
26 12713499 Treatment of breast cancer in countries with limited resources. Breast J 2003 May-Jun 4
27 12722879 Aromatase inhibitors for treatment of postmenopausal patients with breast cancer. Expert Rev Anticancer Ther 2003 Apr 2
28 12727558 The effect of high dehydroepiandrosterone sulfate levels on tamoxifen blockade and breast cancer progression. Am J Surg 2003 May 1
29 12843139 Familial hyperestrogenism in both sexes: clinical, hormonal, and molecular studies of two siblings. J Clin Endocrinol Metab 2003 Jul 1
30 12875605 The current status of aromatase inhibitors in the management of breast cancer. Surg Clin North Am 2003 Aug 1
31 12938779 Aromatase inhibition for the treatment of idiopathic hypogonadotropic hypogonadism in men with premature ejaculation. South Med J 2003 Jun 2
32 14513436 Aromatase inhibitors in early breast cancer treatment. Semin Oncol 2003 Aug 1
33 14535533 Future directions in the endocrine therapy of breast cancer. Breast Cancer Res Treat 2003 1
34 14584060 Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. Cancer 2003 Nov 1 1
35 14623524 Neoadjuvant tamoxifen and aromatase inhibitors: comparisons and clinical outcomes. J Steroid Biochem Mol Biol 2003 Sep 1
36 14623537 'Arimidex' (anastrozole) versus tamoxifen as adjuvant therapy in postmenopausal women with early breast cancer--efficacy overview. J Steroid Biochem Mol Biol 2003 Sep 2
37 14623539 An integrated view of aromatase and its inhibition. J Steroid Biochem Mol Biol 2003 Sep 1
38 14687437 Focus on anastrozole and breast cancer. Curr Med Res Opin 2003 2
39 14693319 Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer. Clin Ther 2003 Nov 1
40 14703069 A review of the efficacy of anastrozole in postmenopausal women with advanced breast cancer with visceral metastases. Breast Cancer Res Treat 2003 Dec 2
41 14734491 Data from the Arimidex, tamoxifen, alone or in combination (ATAC) trial: implications for use of aromatase inhibitors in 2003. Clin Cancer Res 2004 Jan 1 4
42 15083379 Aromatase inhibitors: new endocrine treatment of breast cancer. Semin Reprod Med 2004 Feb 1
43 15109437 Effect of estrogen deprivation on follicle/oocyte maturation and embryo development in mice. Chin Med J (Engl) 2004 Apr 1
44 15125747 The impact of hormone receptor status on the clinical efficacy of the new-generation aromatase inhibitors: a review of data from first-line metastatic disease trials in postmenopausal women. Breast J 2004 May-Jun 1
45 15150604 Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy? Br J Cancer 2004 May 4 2
46 15305403 Breast surgery in the 'Arimidex, Tamoxifen Alone or in Combination' (ATAC) trial: American women are more likely than women from the United Kingdom to undergo mastectomy. Cancer 2004 Aug 15 1
47 15358790 Biochemical and biological characterization of a novel anti-aromatase coumarin derivative. J Biol Chem 2004 Nov 12 1
48 15368322 Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer. Cancer 2004 Sep 15 1
49 15378476 The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach. Cancer 2004 Oct 1 1
50 15380230 Synthesis and evaluation of 4-triazolylflavans as new aromatase inhibitors. Bioorg Med Chem Lett 2004 Oct 18 1