Title : Short-term effects of anastrozole treatment on insulin-like growth factor system in postmenopausal advanced breast cancer patients.

Pub. Date : 2002 Apr

PMID : 11983488






2 Functional Relationships(s)
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1 IGF-1 significantly increased during anastrozole treatment (baseline versus 12 weeks, P=0.031), IGF-2 showed a trend towards an increase, and IGFBP-1 constantly but not significantly decreased; IGFBP-3 did not seem to be affected at all. Anastrozole insulin like growth factor 1 Homo sapiens
2 The anastrozole-induced changes in IGFs and IGFBP-1 appeared to be different in the patients receiving a clinical benefit from those observed in non-responders. Anastrozole insulin like growth factor binding protein 1 Homo sapiens