Acecainide






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1 17895 Procainamide pharmacokinetics in beagles: urinary pH dependency and comparison with n-acetylprocainamide. Res Commun Chem Pathol Pharmacol 1977 Jun 1
2 310748 Long-term antiarrhythmic therapy with N-acetylprocainamide. Clin Pharmacol Ther 1979 Mar 4
3 618730 Antiarrhythmic potency of procainamide and N-acetylprocainamide in rabbits. Eur J Pharmacol 1978 Jan 1 1
4 872496 Cumulation of N-acetylprocainamide, an active metabolite of procainamide, in patients with impaired renal function. Clin Pharmacol Ther 1977 Jul 1
5 975731 Hemodialysis for severe procainamide toxicity: clinical and pharmacokinetic observations. Clin Pharmacol Ther 1976 Nov 1
6 1263131 Correlation of the electrophysiological and antiarrhythmic properties of the N-acetyl metabolite of procainamide with plasma and tissue drug concentrations in the dog. J Pharmacol Exp Ther 1976 Apr 1
7 1384320 Combined high-efficiency hemodialysis and charcoal hemoperfusion in severe N-acetylprocainamide intoxication. Am J Kidney Dis 1992 Oct 1
8 2187866 Characterization of an insulin receptor mutant lacking the subunit processing site. J Biol Chem 1990 May 25 2
9 2410877 Torsades de pointes due to n-acetylprocainamide. Pacing Clin Electrophysiol 1985 Jul 1
10 2416904 Circadian changes in procainamide and N-acetylprocainamide kinetics in the rat. J Pharm Pharmacol 1985 Sep 1
11 2424305 Procainamide toxicity in a patient with acute renal failure. Am J Kidney Dis 1986 Jun 1
12 2431636 Pharmacokinetics of procainamide hydrochloride in dogs. Am J Vet Res 1986 Nov 1
13 2439251 Effect kinetics of N-acetylprocainamide-induced QT interval prolongation. Clin Pharmacol Ther 1987 Jul 1
14 2457345 Comparison of the pharmacokinetic and pharmacodynamic properties of procainamide and N-acetylprocainamide. Angiology 1988 Jul 1
15 2474402 Pharmacokinetics of N-acetylprocainamide in patients profiled with a stable isotope method. Clin Pharmacol Ther 1989 Aug 1
16 2479226 [A new anti-arrhythmia drug. II. Comparative studies of the effects of a new acyl derivative of procainamide, procainamide and N-acetylprocainamide on blood pressure and the electrocardiogram in rabbits]. Acta Pol Pharm 1989 1
17 2483600 [New anti-arrhythmia drug. III. Comparative studies of the effects of N-propionylprocainamide, procainamide and N-acetylprocainamide on hemodynamics and cardiac blood flow]. Acta Pol Pharm 1989 1
18 6084435 Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. Ann N Y Acad Sci 1984 1
19 6156049 Intravenous N-acetylprocainamide disposition kinetics in coronary artery disease. Clin Pharmacol Ther 1980 Jul 1
20 6161089 Pharmacokinetic studies of procainamide (PA) and N-acetylprocainamide (NAPA) in healthy subjects. Int J Clin Pharmacol Ther Toxicol 1980 Jun 1
21 6167356 N-acetylprocainamide induced changes in refractoriness and monophasic action potentials of the dog heart in situ. Cardiovasc Res 1981 Mar 1
22 6175815 Kinetic analysis of the vasodilator and ganglionic blocking actions of N-acetylprocainamide. J Cardiovasc Pharmacol 1982 Mar-Apr 1
23 6179685 N-Acetylprocainamide kinetics and clinical response during repeated dosing. Clin Pharmacol Ther 1982 Sep 1
24 6189384 Electrophysiologic properties and antiarrhythmic mechanisms of intravenous N-acetylprocainamide in patients with ventricular dysrhythmias. Am Heart J 1983 May 1
25 6204527 Use of procainamide in chronic ambulatory peritoneal dialysis: report of a case. Am J Kidney Dis 1984 Jul 1
26 6206104 Torsade de pointes induced by N-acetylprocainamide. J Am Coll Cardiol 1984 Sep 1
27 6261406 Procainamide and peripheral neuropathy. South Med J 1981 Apr 1
28 7585564 Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7ras cells in vitro and in nude mice. Cancer Res 1995 Nov 15 1
29 7691251 Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia. Blood 1993 Oct 1 1
30 7829265 Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells. Int J Cancer 1995 Feb 8 3
31 8180967 Induction of myogenic differentiation in a human rhabdomyosarcoma cell line by phenylacetate. Cancer Lett 1994 Apr 1 1
32 8202632 Glucocorticoid induction of hepatic acetyl CoA:arylamine N-acetyltransferase activity in the rat. Res Commun Chem Pathol Pharmacol 1994 Feb 1
33 8477118 Possible case of procainamide-induced intrahepatic cholestatic jaundice. Ann Pharmacother 1993 Apr 1
34 8486788 Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate. J Clin Invest 1993 May 1
35 8844445 Pharmacokinetic and pharmacodynamic comparisons of twice daily and four times daily formulations of procainamide in patients with frequent ventricular premature depolarization. J Clin Pharmacol 1996 Jul 1
36 9067263 Tumor growth inhibition, apoptosis, and Bcl-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination. Cancer Res 1997 Mar 15 1
37 9164413 Genotyping of N-acetylation polymorphism and correlation with procainamide metabolism. Clin Pharmacol Ther 1997 May 1
38 9389730 Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest 1997 Dec 1 7
39 9443381 Improved high-performance liquid chromatographic assay for the determination of procainamide and its N-acetylated metabolite in plasma: application to a single-dose pharmacokinetic study. J Chromatogr Sci 1998 Jan 1
40 9485559 Effect of age, gender, and race on steady state procainamide pharmacokinetics after administration of procanbid sustained-release tablets. Ther Drug Monit 1998 Feb 1
41 9511735 Transcriptional upregulation of retinoic acid receptor beta (RAR beta) expression by phenylacetate in human neuroblastoma cells. Exp Cell Res 1998 Feb 25 4
42 9673780 The influence of moderate and chronic exercise training on the pharmacokinetics of procainamide and N-acetylprocainamide. Biopharm Drug Dispos 1998 Jul 1
43 9703924 Sodium phenylacetate modulates the synthesis of autocrine and paracrine growth factors secreted by breast cancer cell lines. Anticancer Res 1998 Jul-Aug 1
44 10076540 Cellular distribution of N-acetyltransferase activity in the rat small intestine. Biochem Pharmacol 1998 May 1 1
45 11029704 Transactivation of the Brassica napus napin promoter by ABI3 requires interaction of the conserved B2 and B3 domains of ABI3 with different cis-elements: B2 mediates activation through an ABRE, whereas B3 interacts with an RY/G-box. Plant J 2000 Oct 2
46 11939777 The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement. Biochemistry 2002 Apr 16 2
47 12089365 cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney. J Am Soc Nephrol 2002 Jul 1
48 12646656 Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J Immunol 2003 Apr 1 6
49 16581519 Nap1 regulates Dictyostelium cell motility and adhesion through SCAR-dependent and -independent pathways. Curr Biol 2006 Apr 4 1
50 16839052 Characterization of the conformational probability of N-acetyl-phenylalanyl-NH2 by RHF, DFT, and MP2 computation and AIM analyses, confirmed by jet-cooled infrared data. J Phys Chem A 2005 Jun 23 1