Pub. Date : 1998 Feb 25
PMID : 9511735
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Our studies indicated that NaPA can impact on the RA differentiation program by upregulating nuclear retinoic acid receptor-beta (RAR beta) expression. | Acecainide | retinoic acid receptor beta | Homo sapiens |
2 | Our studies indicated that NaPA can impact on the RA differentiation program by upregulating nuclear retinoic acid receptor-beta (RAR beta) expression. | Acecainide | retinoic acid receptor beta | Homo sapiens |
3 | In contrast, NaPA was able to specifically activate a reporter gene construct (delta SV beta RE-CAT) which contains a retinoic acid response element (RARE beta) that is located in the RAR beta promoter. | Acecainide | retinoic acid receptor beta | Homo sapiens |
4 | Taken together, our findings suggest that induction of RAR beta by NaPA is regulated at the level of transcription and mediated through the retinoic acid response element, RARE beta. | Acecainide | retinoic acid receptor beta | Homo sapiens |