Camptothecin






1295 Article(s)
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1 988022 Mitogen receptors in chick embryo fibroblasts. Kinetics, specificity, unmasking, and synthesis of 125I-insulin binding sites. J Biol Chem 1976 Oct 25 1
2 1174509 Regulation of ornithine decarboxylase in 3T3 cells by putrescine and spermidine: indirect evidence for translational control. Biochemistry 1975 Oct 7 1
3 1309380 A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer. J Clin Oncol 1992 Jan 1
4 1310495 Potentiation of radiation response in human carcinoma cells in vitro and murine fibrosarcoma in vivo by topotecan, an inhibitor of DNA topoisomerase I. Int J Radiat Oncol Biol Phys 1992 1
5 1312349 Analysis of topoisomerase I and II cleavage sites on the Drosophila actin and Hsp70 heat shock genes. Biochemistry 1992 Mar 10 1
6 1312900 The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B. Cancer Res 1992 Apr 1 2
7 1319161 Characterization of camptothecin-resistant Chinese hamster lung cells. Biochem Pharmacol 1992 Jun 9 2
8 1336489 Potentiation of topoisomerase I and II inhibitors cell killing by tumor necrosis factor: relationship to DNA strand breakage formation. Jpn J Cancer Res 1992 Nov 1
9 1383716 Nalidixic acid-resistant V79 cells with reduced DNA topoisomerase II activity and amplification prone phenotype. Mutat Res 1992 Oct 1
10 1426041 Characterization and cellular localization of nucleophosmin/B23 in HeLa cells treated with selected cytotoxic agents (studies of B23-translocation mechanism). Exp Cell Res 1992 Nov 4
11 1596908 Cell cycle-related expression of p120 nucleolar antigen in normal human lymphocytes and in cells of HL-60 and MOLT-4 leukemic lines: effects of methotrexate, camptothecin, and teniposide. Cancer Res 1992 Jun 15 2
12 1602973 Micronucleus induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice. Mutagenesis 1992 May 1
13 1650187 A DNA topoisomerase I inhibitor blocks the differentiation of rat granulosa cells induced by follicle-stimulating hormone. Biochem J 1991 Jul 15 1
14 1668830 Regulation of topoisomerase I and II activities by cyclic nucleotide- and phospholipid-dependent protein kinases. Effects of interactions between the two transduction pathways. Receptor 1991 1
15 1680548 Induction of in vitro differentiation of mouse embryonal carcinoma (F9) cells by inhibitors of topoisomerases. Cancer Res 1991 Oct 1 1
16 1682041 Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells. Cancer Res 1991 Nov 15 4
17 1737386 Camptothecin induces differentiation and stimulates the expression of differentiation-related genes in U-937 human promonocytic leukemia cells. Cancer Res 1992 Mar 1 10
18 1742737 Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells. Cancer Res 1991 Dec 15 3
19 1804390 Augmentation of antiproliferative activity of CPT-11, a new derivative of camptothecin, by tumor necrosis factor against proliferation of gynecologic tumor cell lines. Anticancer Drugs 1991 Oct 1
20 1847484 Autonomous parvovirus DNA replication requires topoisomerase I and its activity is increased during infection. J Virol 1991 Mar 1
21 1848545 Topoisomerase inhibitors have potent differentiation-inducing activity for human and mouse myeloid leukemia cells. Jpn J Cancer Res 1991 Feb 1
22 2012400 [An early phase II study of CPT-11 in gynecologic cancers. Research Group of CPT-11 in Gynecologic Cancers]. Gan To Kagaku Ryoho 1991 Apr 1
23 2032244 Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin. Cancer Res 1991 Jun 1 1
24 2153054 Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities. Cell 1990 Jan 12 2
25 2158396 Potentiation of topoisomerase inhibitor-induced DNA strand breakage and cytotoxicity by tumor necrosis factor: enhancement of topoisomerase activity as a mechanism of potentiation. Cancer Res 1990 May 1 2
26 2170010 Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody. Cancer Res 1990 Nov 1 2
27 2170526 Synergistic interactions between tumor necrosis factor and inhibitors of DNA topoisomerase I and II. J Immunol 1990 Nov 1 1
28 2174738 Elevated expression of DNA topoisomerase II in camptothecin-resistant human tumor cell lines. Cancer Res 1990 Dec 15 3
29 2302199 Induction of differentiation of human and mouse myeloid leukemia cells by camptothecin. Biochem Biophys Res Commun 1990 Jan 15 2
30 2308592 DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells. Mutat Res 1990 Mar 2
31 2478139 Evidence for the participation of topoisomerases I and II in cadmium-induced metallothionein expression in Chinese hamster ovary cells. Anticancer Drug Des 1989 Aug 1
32 2545341 DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues. Cancer Res 1989 Aug 15 1
33 2548490 Transcriptional inhibitors affecting topoisomerase II induce changes in histone methylation patterns similar to those induced by heat shock. Biochem Biophys Res Commun 1989 Aug 15 1
34 2552999 Stimulation of intracellular topoisomerase I activity by vasopressin and thrombin. Differential regulation by pertussis toxin. Biochem J 1989 Sep 1 3
35 2555773 Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene. Nucleic Acids Res 1989 Nov 11 3
36 2557085 Topoisomerase-targeting antitumor drugs. Biochim Biophys Acta 1989 Dec 17 1
37 2819725 Association of topoisomerase I with transcriptionally active loci in Drosophila. NCI Monogr 1987 2
38 2819731 Camptothecin inhibits hsp 70 heat-shock transcription and induces DNA strand breaks in hsp 70 genes in Drosophila. NCI Monogr 1987 5
39 2839226 Regulation of Xenopus laevis DNA topoisomerase I activity by phosphorylation in vitro. Biochemistry 1988 May 3 1
40 2846151 Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I. Cancer Res 1988 Nov 15 3
41 3028614 Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells. Cancer Res 1987 Apr 1 1
42 3031452 Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin. Mol Cell Biol 1987 Jan 3
43 3033639 Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene. Proc Natl Acad Sci U S A 1987 May 3
44 5289246 Ribosome formation is blocked by camptothecin, a reversible inhibitor of RNA synthesis. Proc Natl Acad Sci U S A 1971 Dec 1
45 7240210 Regulation of acetylcholinesterase activity by nerve growth factor. Role of transcription and dissociation from effects on proliferation and neurite outgrowth. J Biol Chem 1981 Jun 25 1
46 7510956 Topoisomerase I-inhibition enhances vitamin D-responsive expression of the receptor for lipopolysaccharide binding protein CD 14. Biochem Biophys Res Commun 1994 Mar 15 3
47 7540951 Expression of a deletion mutant of the E2F1 transcription factor in fibroblasts lengthens S phase and increases sensitivity to S phase-specific toxins. Cancer Res 1995 Jul 1 2
48 7603986 SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I. Proc Natl Acad Sci U S A 1995 Jul 3 7
49 7678901 Higher G2 sensitivity to the induction of chromosomal damage in the CHO mutant EM9 than in its parental line AA8 by camptothecin, an inhibitor of DNA topoisomerase I. Mutat Res 1993 Feb 3
50 7688089 Cytogenetic effects of inhibition of topoisomerase I or II activities in the CHO mutant EM9 and its parental line AA8. Mutat Res 1993 Aug 1