Title : Nalidixic acid-resistant V79 cells with reduced DNA topoisomerase II activity and amplification prone phenotype.

Pub. Date : 1992 Oct

PMID : 1383716






1 Functional Relationships(s)
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1 These lines were also cross-resistant to the eukaryotic topoisomerase II inhibitors etoposide and adriamycin, but showed the same level of sensitivity as the parental line to the DNA topoisomerase I inhibitor camptothecin. Camptothecin DNA topoisomerase 1 Cricetulus griseus