| 1251 | 33529438 | Targeting DNA damage response pathways to activate the STING innate immune signaling pathway in human cancer cells. | FEBS J | 2021 Aug |
4 |
| 1252 | 33536335 | SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors. | Proc Natl Acad Sci U S A | 2021 Feb 9 |
6 |
| 1253 | 33559345 | Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli-1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB × NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells. | Arthritis Rheumatol | 2021 Aug |
3 |
| 1254 | 33563179 | In Vitro Metabolism of E2, G2: Novel Bile Acid-Coupling Camptothecin Analogues, in Rat Liver Microsomes. | Recent Pat Anticancer Drug Discov | 2021 |
1 |
| 1255 | 33582946 | Leptin activates Akt in oesophageal cancer cells via multiple atorvastatin-sensitive small GTPases. | Mol Cell Biochem | 2021 Jun |
2 |
| 1256 | 33583643 | Nucleosome assembly protein 1-like 4, a new therapeutic target for proliferation and invasion of melanoma cells. | J Dermatol Sci | 2021 Apr |
1 |
| 1257 | 33704464 | DOCK7 protects against replication stress by promoting RPA stability on chromatin. | Nucleic Acids Res | 2021 Apr 6 |
2 |
| 1258 | 33714537 | Target identification and drug discovery by data-driven hypothesis and experimental validation in ovarian endometriosis. | Fertil Steril | 2021 Aug |
1 |
| 1259 | 33774201 | Photo-responsive prodrug nanoparticles for efficient cytoplasmic delivery and synergistic photodynamic-chemotherapy of metastatic triple-negative breast cancer. | Acta Biomater | 2021 May |
3 |
| 1260 | 33785416 | The effect of hypergravity in intestinal permeability of nanoformulations and molecules. | Eur J Pharm Biopharm | 2021 Jun |
1 |
| 1261 | 33812400 | [Effect of Bmi-1 Expression on Chemotherapy Sensitivity in THP-1 Cells]. | Zhongguo Shi Yan Xue Ye Xue Za Zhi | 2021 Apr |
2 |
| 1262 | 33868235 | Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects <i>via</i> Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways <i>In Vivo</i> and <i>In Vitro</i>. | Front Immunol | 2021 |
4 |
| 1263 | 33882408 | Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c. | Redox Biol | 2021 Jul |
2 |
| 1264 | 33898327 | Camptothecin Inhibits Neddylation to Activate the Protective Autophagy Through NF-<i>κ</i>B/AMPK/mTOR/ULK1 Axis in Human Esophageal Cancer Cells. | Front Oncol | 2021 |
4 |
| 1265 | 34049076 | PARP1-mediated PARylation of TonEBP prevents R-loop-associated DNA damage. | DNA Repair (Amst) | 2021 Aug |
4 |
| 1266 | 34138544 | Correction to Bifunctional Cytochrome P450 Enzymes Involved in Camptothecin Biosynthesis. | ACS Chem Biol | 2021 Jul 16 |
1 |
| 1267 | 34159519 | Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs. | Oncol Ther | 2021 Dec |
1 |
| 1268 | 34178646 | Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma. | Front Oncol | 2021 |
3 |
| 1269 | 34201500 | Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric <i>MLL</i>-Rearranged Acute Lymphoblastic Leukemia. | Biomedicines | 2021 Jun 23 |
1 |
| 1270 | 34205418 | Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG. | Int J Mol Sci | 2021 Jun 19 |
2 |
| 1271 | 34226554 | DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination. | Nat Commun | 2021 Jul 5 |
1 |
| 1272 | 34337875 | Integrated pan-cancer of AURKA expression and drug sensitivity analysis reveals increased expression of AURKA is responsible for drug resistance. | Cancer Med | 2021 Sep |
1 |
| 1273 | 34385682 | Immunogenic camptothesome nanovesicles comprising sphingomyelin-derived camptothecin bilayers for safe and synergistic cancer immunochemotherapy. | Nat Nanotechnol | 2021 Oct |
3 |
| 1274 | 34496254 | Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. | Cell Rep | 2021 Sep 7 |
3 |
| 1275 | 34500463 | XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase. | Nucleic Acids Res | 2021 Sep 27 |
2 |
| 1276 | 34519602 | Design and evaluation of glutathione responsive glycosylated camptothecin nanosupramolecular prodrug. | Drug Deliv | 2021 Dec |
1 |
| 1277 | 34547508 | A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo. | Eur J Med Chem | 2021 Dec 15 |
1 |
| 1278 | 34572735 | Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance. | Cancers (Basel) | 2021 Sep 7 |
2 |
| 1279 | 34649567 | Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling. | Mol Cancer | 2021 Oct 14 |
2 |
| 1280 | 34694772 | Real-Time Spatial and Temporal Analysis of the Translocation of the Apoptosis-Inducing Factor in Cells. | ACS Chem Biol | 2021 Nov 19 |
4 |
| 1281 | 34819354 | Replication protein A associates with nucleolar R loops and regulates rRNA transcription and nucleolar morphology. | Genes Dev | 2021 Dec 1 |
2 |
| 1282 | 34825166 | Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin. | Int J Pharm X | 2021 Dec |
2 |
| 1283 | 35053556 | A Small Molecule-Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α<sub>V</sub>ß<sub>3</sub> Binder for the Treatment of Multiple Cancer Types. | Cancers (Basel) | 2022 Jan 13 |
1 |
| 1284 | 35064653 | Dynamic Adjust of Non-Radiative and Radiative Attenuation of AIE Molecules Reinforces NIR-II Imaging Mediated Photothermal Therapy and Immunotherapy. | Adv Sci (Weinh) | 2022 Mar |
4 |
| 1285 | 35087822 | Pharmacological Targeting of STING-Dependent IL-6 Production in Cancer Cells. | Front Cell Dev Biol | 2021 |
2 |
| 1286 | 35111947 | Injectable hyaluronic acid hydrogels encapsulating drug nanocrystals for long-term treatment of inflammatory arthritis. | Bioeng Transl Med | 2022 Jan |
1 |
| 1287 | 35163672 | Nanocarrier-Based Delivery of SN22 as a Tocopheryl Oxamate Prodrug Achieves Rapid Tumor Regression and Extends Survival in High-Risk Neuroblastoma Models. | Int J Mol Sci | 2022 Feb 3 |
1 |
| 1288 | 35192728 | Poloxamer-linked prodrug of a topoisomerase I inhibitor SN22 shows efficacy in models of high-risk neuroblastoma with primary and acquired chemoresistance. | FASEB J | 2022 Mar |
3 |
| 1289 | 35202387 | Camptothecin effectively treats obesity in mice through GDF15 induction. | PLoS Biol | 2022 Feb |
2 |
| 1290 | 35219381 | Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation. | Mol Cell | 2022 Apr 7 |
2 |
| 1291 | 35291312 | Cleavage-defective Topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability. | Microb Cell | 2022 Mar 7 |
4 |
| 1292 | 35345325 | A Yeast-Based Screening System for Differential Identification of Poisons and Suppressors of Human Topoisomerase I. | Front Biosci (Landmark Ed) | 2022 Mar 9 |
1 |
| 1293 | 35357810 | Sequential Ultrasound-Triggered and Hypoxia-Sensitive Nanoprodrug for Cascade Amplification of Sonochemotherapy. | ACS Nano | 2022 Mar 31 |
1 |
| 1294 | 35430566 | SLFN12 Over-expression Sensitizes Triple Negative Breast Cancer Cells to Chemotherapy Drugs and Radiotherapy. | Cancer Genomics Proteomics | 2022 May-Jun |
7 |
| 1295 | 35456987 | Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. | Int J Mol Sci | 2022 Apr 10 |
4 |