Title : Expression of arylamine N-acetyltransferase in human intestine.

Pub. Date : 1998 Mar

PMID : 9577349






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Other substrates include the sulphonamide 5-aminosalicylic acid (5-ASA), which is an NAT1 specific substrate; N-acetylation of 5-ASA is a major route of metabolism. Mesalamine N-acetyltransferase 1 Homo sapiens
2 AIMS: To investigate NAT expression in apparently healthy human intestines in order to understand the possible role of NAT in colorectal cancer and in the therapeutic response to 5-ASA. Mesalamine bromodomain containing 2 Homo sapiens
3 CONCLUSIONS: The interindividual variation in NAT1 and NAT2 in the colon could affect how individuals respond to exposure to specific NAT substrates including carcinogens and 5-ASA. Mesalamine N-acetyltransferase 1 Homo sapiens
4 CONCLUSIONS: The interindividual variation in NAT1 and NAT2 in the colon could affect how individuals respond to exposure to specific NAT substrates including carcinogens and 5-ASA. Mesalamine N-acetyltransferase 2 Homo sapiens
5 CONCLUSIONS: The interindividual variation in NAT1 and NAT2 in the colon could affect how individuals respond to exposure to specific NAT substrates including carcinogens and 5-ASA. Mesalamine bromodomain containing 2 Homo sapiens