Pub. Date : 1998 Mar
PMID : 9577349
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Other substrates include the sulphonamide 5-aminosalicylic acid (5-ASA), which is an NAT1 specific substrate; N-acetylation of 5-ASA is a major route of metabolism. | Mesalamine | N-acetyltransferase 1 | Homo sapiens |
2 | AIMS: To investigate NAT expression in apparently healthy human intestines in order to understand the possible role of NAT in colorectal cancer and in the therapeutic response to 5-ASA. | Mesalamine | bromodomain containing 2 | Homo sapiens |
3 | CONCLUSIONS: The interindividual variation in NAT1 and NAT2 in the colon could affect how individuals respond to exposure to specific NAT substrates including carcinogens and 5-ASA. | Mesalamine | N-acetyltransferase 1 | Homo sapiens |
4 | CONCLUSIONS: The interindividual variation in NAT1 and NAT2 in the colon could affect how individuals respond to exposure to specific NAT substrates including carcinogens and 5-ASA. | Mesalamine | N-acetyltransferase 2 | Homo sapiens |
5 | CONCLUSIONS: The interindividual variation in NAT1 and NAT2 in the colon could affect how individuals respond to exposure to specific NAT substrates including carcinogens and 5-ASA. | Mesalamine | bromodomain containing 2 | Homo sapiens |