Protein Name N-acetyltransferase 1
Organism Homo sapiens
Gene ID 9
Gene Symbol

NAT1

UniProt P18440 (ARY1_HUMAN), Q400J6 (Q400J6_HUMAN), F5H5R8 (F5H5R8_HUMAN)
Relationships Total Number of functionally related compound(s) : 266
Total Number of Articles : 275
Description

N-acetyltransferase 1

Gene Summary

This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

synonyms
  • arylamine N-acetyltransferase 1
  • N-acetyltransferase 1 (arylamine N-acetyltransferase)
  • N-acetyltransferase type 1
Click to show/hide the synonyms
Properties